Posted May 08, 2008
Senior Pathologist
Novartis, East Hanover, NJ

Welcome to Novartis - the company that considers its employees to be its greatest asset.

Good Business.

Great Opportunities.

How do you spend your day? Are you passionate about what you do? At Novartis, our focus is clear, our purpose defined. We're part of a team that's making a difference in the quality of people's lives. Think What's Possible.

Description:
The incumbent is responsible for generating and evaluating pathology data for assigned studies and accomplishes this through direct/indirect supervision of individuals assigned to studies. The incumbent is expected to sit on scientific boards, project teams, advisory committees and may be asked to function as project team representative for Preclinical Safety. A strong toxicologic pathology background in a GLP environment is preferred. The incumbent is expected to participate in study design and in the evaluation and implementation of new procedures to improve operations. Current knowledge of recent advances and new equipment/procedures is important to achieve optimum results. May be assigned to projects with standard design and/or those requiring an appropriate level of interpretive experience and knowledge. At the conclusion of the study, the incumbent is expected to participate in the data review/analyses and determine target organ toxicity. Performs other duties as assigned by management.

Qualifications:
DVM/MD degree (or equivalent) with board certification in Pathology (e.g., ACVP). graduate training in pathology, or PhD in veterinary pathology . Board certification in related fields is preferred. (e.g., ACVP, DABT). Ability to interpret pathology results and write reports and scientific manuscripts. Ability to supervise other personnel, when necessary. Novartis is committed to embracing and leveraging diverse backgrounds.

Novartis is an equal opportunity employer M/F/D/V.

Posted May 08, 2008
Veterinary Pathologists - Req. # 48536
GlaxoSmithKline

At GlaxoSmithKline, we understand that the fewer barriers there are, the better our work can be. That’s why we encourage our nearly 50-strong team of veterinary pathologists to take a more autonomous role when assessing the safety profile of our key compounds. It means they enjoy a greater sense of ownership in helping to take new assets to market.

Then there’s the unprecedented level of investment, the international profile of our products, and a pipeline of over 150 pharmaceutical and vaccine projects that’s the envy of the industry. Of course, the size of the team itself also gives pathologists the freedom to grow and develop, as does the opportunity to work across a number of therapeutic areas, especially respiratory, inflammation, oncology, neurology and biotechnology. In short, for highly motivated veterinary graduates experienced in pathology, there’s really no better place to be.

Responsible for assessing the safety of novel compounds, you’ll undertake routine and investigative studies to evaluate drug candidates within the Regulatory environment, while also supporting a variety of Discovery Research programs. As well as applying your histopathology expertise, you’ll get involved in molecular pathology and mechanistic investigations. In addition, you’ll enjoy the opportunity to build your skills in drug development as a project team member.

Candidate Requirements:

• DVM, PhD and diplomate status in the ACVP. Prefer experience in drug development and toxicologic and investigative pathology.
• Demonstrated investigative/problem solving skills.
• Experienced or interest in executing preclinical drug development plans. • Clear/concise written and oral communication skills.

Position Responsibilities:

• Provides diagnostic and interpretive toxicologic pathology skills in a GLP environment. • Authors morphological pathology contributions to study reports and comprehensive overviews of preclinical findings. • Interacts with multidisciplinary discovery and development teams of scientists to address drug development needs. • Designs and directs toxicology drug-development plans for product registration. • Interacts with pathology staff. • Champions innovative approaches to resolving toxicologic pathology issues. • Must be willing to adapt to rapidly changing scientific and regulatory environments.

This is a truly remarkable opportunity to develop your career beyond traditional boundaries, and play a central role in the creation of drugs that will enable people around the world to lead longer, healthier, happier lives.

GlaxoSmithKline is dedicated to an innovated workplace and supports you with career long opportunities and learning. We offer a competitive benefits and compensation package designed to attract and retain the very best. For confidential consideration and efficient processing, visit our Web Site: http://www.gsk.com and reference requisition 48536.

Developing talent through equality of opportunity. M/F/D/V

Posted April 11, 2008
Veterinary Pathologist – Req #6872
Roche, Nutley, NJ

Roche is in the midst of one of the most exciting periods in its history. With an array of established products, a healthy line of new products and several exciting launches ahead, Roche is extremely well-positioned to be one of the truly preeminent companies that lead the industry into the 21st century.  If you want to work in a dynamic, challenging environment that capitalizes on your strengths and abilities, please take a few moments to peruse the following opportunity at our Nutley, New Jersey campus.  The pathology group is a key player in the Nutley Non-Clinical Safety Department (NCS), which also includes the disciplines of Toxicology, Drug Metabolism, Pharmacokinetics, Safety Pharmacology and Bioanalytics.

Veterinary Pathologists

The pathology group at Roche Nutley includes discovery, clinical pathology and pathology laboratories, and is responsible for leading and providing input from early discovery to late development of the Company’s therapeutics.   The successful candidate will have the opportunity to get involved with discovery groups and lead pathology input on animal model characterization, efficacy and early screen studies, as well as being responsible for pathology input in study design, clinical and anatomical pathology interpretation of regulatory toxicology studies.  In addition, pathologists in collaboration with pharmacokineticists and toxicologists, represent the department on project teams, which are expected to provide development strategies.  The balance between discovery, regulatory and team management activities is flexible to match the needs and talents of the successful candidate.

As members of a global company, Roche pathologists have ample opportunities to collaborate with other scientists, throughout the organization. In addition, a collegial atmosphere and a state of the art telepathology system offer the possibility to consult with pathologists at other Roche sites and opportunities exist to train at other Roche locations.   Finally, participation in professional organizations, collaboration with academic institutions, presentation of scientific posters at professional meetings, and publication of papers are strongly encouraged and actively supported.

Requirements:

1. This position requires a D.V.M. and a certified training in pathology (ACVP/ECVP), preferably with PhD or proven research experience in related field, and a minimum of 2 to 5 years experience working in a regulatory toxicology environment.  Solid technical knowledge and experience with specialized techniques used in discovery such as immunohistochemistry, immunofluorescence, confocal microscopy, in situ hybridization, electron microscopy, PCR, qPCR, tissue microarrays, laser capture microdissection, transcriptomics..etc.  Excellent communication skills, innovation and commitment, the ability to constantly prioritize regulatory work with Discovery projects and to contribute effectively to a sound, timely decision making process are critical.  

To apply, please submit resume at:

http://careers.roche.com/wms/extern/jobdetail.php?id=mS/J5TNoA8MxtuYu5N54dwgME84u12TgkBNzisi%204Gm0pz1d

Posted March 21, 2008
Principal Scientist - Toxicologist
Genentech, South San Fransicso, CA

For more than 30 years, Genentech has been at the forefront of the biotechnology industry, using human genetic information to develop novel medicines for serious and life-threatening diseases. Today, Genentech is among the world's leading biotech companies, with multiple therapies on the market for cancer and other serious medical conditions. Please take this opportunity to learn about Genentech, where we believe that our employees are our most important asset.

The following opportunity exists in our South San Francisco, CA, headquarters:

Principal Scientist - Toxicologist

Responsibilities:
The Safety Assessment department of Genentech is seeking a Senior Toxicologist with a proven record of drug development and leadership in the area of small molecule pharmaceuticals. As the Safety Assessment Group Leader for Small Molecule Therapeutics, this position will lead a highly talented team of toxicologists in a fast-paced environment to create and execute highly integrated drug development strategies in support of new molecular entities from late-stage research through licensure and life-cycle management. The successful candidate will be a recognized leader and contributor to the small molecule safety assessment field, with a passion for bringing new medicines to patients with unmet medical needs. Toxicologists at Genentech provide scientific leadership and play an active role in the process of drug development. Working in an integrated and collaborative team environment, we lead the safety assessment of Genentech therapeutics by creating a best-evidence synthesis of existing knowledge and comprehensive characterization of toxicological activity. In addition to providing strategic vision for the development of our rapidly expanding small molecule drug development portfolio, position responsibilities include: staffing, mentoring and career development of toxicologists and research associates, scientific leadership in the design and implementation of safety assessment strategies for Genentech's small molecule portfolio and leading or providing support to inter- and intra-departmental initiatives. This is an excellent opportunity for a senior level Toxicologist, with strong scientific, communication and teamwork skills, who is committed to bringing innovative therapies to patients. This position will report to the Associate Director of Toxicology in the department of Safety Assessment.

Requirements:
The candidate must have a Ph.D. or equivalent experience in Toxicology with a minimum of 12 years of professional experience in the pharmaceutical industry. Board certification in toxicology is highly desirable. This individual must be dynamic and creative with an established record of experience and accomplishment in driving drug development and safety assessment for small molecule pharmaceuticals, particularly in the area of oncology. Excellent interpersonal, written and verbal communication skills and very strong management experience are required. The incumbent must have evidence of significant contribution to the field, and direct interaction with regulatory authorities. The proven ability to build and sustain productive internal and external cross-functional collaborations is also required.

Genentech is dedicated to fostering an environment that is inclusive and encourages diversity of thought, style, skills and perspective. To learn more about our current opportunities, please visit: http://www.gene.com/gene/careers/ and reference Req. #1000022435. Please use "Web–STP" when a "source" is requested. Genentech is an Equal Opportunity Employer.

Posted March 5, 2008
Board-Certified Veterinary Pathologist
The Jackson Laboratory, Bar Harbor, ME

The Jackson Laboratory is seeking a Board-Certified Veterinary Pathologist with extensive experience in the pathology of laboratory mice to join its Laboratory Animal Health Services (LAHS) department in Bar Harbor, Maine. LAHS provides a variety of veterinary, diagnostic, and quality management services supporting the Research, Resource, and Mouse Service divisions of The Jackson Laboratory facilities in Bar Harbor and West Sacramento, California.

The pathologist will provide anatomic pathology support for the internal sick mouse/health surveillance program, consult and read studies for off campus clients, participate in the educational mission of the Laboratory, and provide consultation to the Laboratory's scientific staff. In addition, the pathologist will work with the Manager, Necropsy Service to develop and refine standard operating procedures for the Necropsy Service and to provide guidance in necropsy techniques and procedures for the pathology technicians. Up to 20% of the pathologist's time may be devoted to personal and/or collaborative research. This position requires excellent interpersonal and communication skills and the ability to work in a diverse and energetic scientific community. For consideration please submit a curriculum vitae, the names and addresses of three professional references and a letter describing your qualifications for the position to Dr. Oded Foreman, The Jackson Laboratory, 600 Main St, Bar Harbor, ME 04609.

Posted February 28, 2008
Toxicologic Pathologist
Intergrated Laboratory System, Inc., RTP, NC

Integrated Laboratory Systems, Inc. is a growing R&D organization that provides comprehensive health and environmental research and testing services and associated bioinformatics support. We are headquartered in RTP and have been serving the public and private sectors since 1985. ILS provides a competitive salary and benefits package and attempt to develop the full potential of our work force by providing training and opportunities for career enhancement. We provide a work atmosphere that is safe, healthy, secure, and conscious of long-term family and community goals. We are currently seeking a qualified, board eligible professional in the discipline of pathology.

Toxicologic Pathologist
Position Description: Full-time position. Responsibilities will include: Evaluating both subchronic and chronic toxicity/carcinogenicity studies in rats and mice and peer reviewing pathology data and reports. Organizing, coordinating, and conducting NTP peer review pathology working groups (PWG) and preparation of PWG summary reports. Serve as study pathologist on research studies providing gross and histopathological evaluations and preparing pathology reports. Performing quality assessment of pathology specimens. Working in multidisciplinary teams. Interacting with clients; Business Development activities. Veterinarian issues input. Work in a team environment with a professional and positive attitude. Other duties as needed.

Qualifications:
D.V.M. or equivalent with experience in rodent toxicological pathology. Board eligible. Pathology and histology expertise. Excellent communication skills. Computer literate.

If you would like further information regarding the position please contact Dr. Pamela Blackshear, Division Director, Comparative Molecular Pathology Division, (919) 281-1110 ext. 727.

ILS offers competitive salaries and a complete benefits package. Interested candidates should apply online at: http://www.ils-inc.com/jobs.asp

Integrated Laboratory Systems, Inc. provides equal employment opportunity to all individuals without regard to race, color, religion, gender, national origin, age, disability, or veteran status.

Posted February 26, 2008
Pathologist Director
Amgen, Thousand Oaks, CA

Amgen discovers, develops and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science’s promise by bringing safe, effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives.

CAREER OPPORTUNITIES

Pathologist Director – Thousand Oaks, CA (NB50182719*)
Reporting to the Director of Pathology, the non-supervisory role is to provide expert pathology and toxicology input across the drug discovery and development portfolio. Key activities will include: leading pathology input into drug discovery and development teams; conducting and peer-reviewing pathology evaluations in connection with toxicology studies; collaborating with colleagues across the toxicology department to produce drug development strategies; leading pathology input in project regulatory interactions; leading pathology input into project licensing activities; leading the pathology component of problem-solving collaborations with toxicology scientists across the toxicology and discovery departments; and participating and presenting at pathology cross site slide conferences and meetings. Involvement in external societies and continuing scientific development will be encouraged and strongly supported. The deliverable is the internal and external communication of quality pathology assessment and interpretation of discovery and development animal studies, with particular emphasis on scientific and mechanistic understanding. There is considerable scope for expanding the role, for example acting as a project team representative on drug development teams.

Basic Qualifications:
This position requires a DVM plus PhD. Board certification by ACVP, ECVP, RCPath or equivalent. Three years experience as a pathologist in industry and three years experience in the application of pathology in GLP drug development.

Preferred Qualifications:
Preferred qualifications include five years experience as a pathologist in industry and five years experience in the application of pathology in GLP drug development; a publication track record in toxicologic pathology; experience of application of pathology in drug discovery; a track record of external representation; thorough understanding of the drug development process; ability to present and represent the departments at cross-functional venues; strong scientific skills in interpretation of pathogenesis of lesions; strong influencing skills.

Please apply to this position by visiting www.amgen.com/careers to submit your resume. Please reference job number NB50182719*

Posted January 31, 2008
Scientific Director
Abbott Laboratories, Illinois, Abbott Park

Follow your aspirations to Abbott for diverse opportunities, competitive salaries, great benefits, a 401(k) retirement savings plan, a company paid pension plan and profit sharing, all with a company providing the growth and strength to build your future.

Description:
Based on experience, position may be hired at either a grade 22 or 21. The role of the Scientific Director is to provide expertise and consultation in the area of Preclinical Safety for multiple drug candidates through all phases of preclinical and clinical drug development. Position serves as a key member of Discovery and Development Teams to ensure that Preclinical Safety strategy is aligned closely with clinical and regulatory development strategy. Although not expected to be an expert in all fields of Preclinical Safety, Scientific Directors must have the expertise to work with multidisciplinary teams (toxicology, pathology, metabolism, pharmacokinetics, safety pharmacology, CMC) and serves as a core facilitator for resolution of issues. The Scientific Director provides technical and scientific expertise and leadership in the identification and resolution of complex problems within Global Preclinical Safety. Major areas of responsibility are within defined therapeutic areas and preference will be given to individuals with experience in development of oncology products, however experience in neuroscience, immunologic products or biologics is also of interest.

Essential Work Activities

1. The Scientific Director recommends and takes an active role in the planning of safety studies and does so through interactions with team members from toxicology, pathology, pharmacokinetics, metabolism and drug analysis to ensure optimal compound evaluation.
2. Anticipates, recognizes and resolves scientific and technical problems that are encountered during various phases of compound evaluation.
3. Monitors development of competitor compounds and regulatory opinion in given area.
4. Integrates data across disciplines to draw new or extended conclusions and develop alternative scenarios as needed.
5. Provides complex communications under tight timelines. Can communicate relevant facts clearly and concisely. Serves as a facilitator to ensure that appropriate individuals are involved in key decision-making and interpretive efforts. Develops and/or participates in presentations for internal and external venues, to include US and international regulatory agencies.

Qualifications:
Doctoral degree highly preferred with 10 years or more of relevant outstanding experience to effectively manage/direct global teams and all related activities with respect to science, technology, quality, regulatory and compliance requirements related to safety evaluation of drug products. Advanced degree in an appropriate scientific field that is directly applicable to preclinical safety (including, but not limited to toxicology or pathology). Board certification in that field is highly desirable.

Key experience attributes:

1. Technical expertise in drug development, including discovery, development, and regulatory requirements as they relate to pharmaceutical toxicology
2. Experience presenting to senior company management and US or international regulatory agencies
3. Experience with evaluation of compounds in various phases of development. Preference for individuals with experience in oncology product development
4. Excellent verbal and written communications skills

Abbott welcomes and encourages diversity in our workforce. EEO/AA

Apply Online at:
http://appclix.postmasterlx.com/track.html?pid=402881bd15cb73fa0115cf2d8c4f15ac&source=toxicology&p=codes=TOX

Posted January 3, 2008
Toxicologic Pathologist
RCC, Ltd., Itingen/Switzerland
Reference Req. #2-861

RCC is a global Contract Research Organization of the Harlan Sprague Dawley Inc. group with its headquarters in Itingen, close to Basel/Switzerland. We have further subsidiaries in Germany, Spain, India, Canada and Japan. Today, RCC group is one of Europe's leading contract research and regulatory consulting organizations employing nearly 1,000 staff members. For the enhancement of our team in the United Kingdom or in Switzerland, we have an opening (immediate or by agreement) for a Toxicologic Pathologist.

Job Description
Toxicologic Pathologist / 2-861

Responsibilities

We are seeking a toxicologic pathologist to serve as study pathologist on studies ranging from acute and efficacy studies to oncogenicity studies. This role involves working in a collaborative team environment and providing expertise in the design, conduct and data analysis of GLP toxicology studies. You will provide descriptions and interpret summaries of clinical pathology data of gross and histopathologic changes observed in laboratory and farm animals given new drug candidates. Responsibilities will include scientific and administrative management of the pathology department laboratory.

Profile/Qualifications

This position requires a DVM or MD. Preferred is a pathologist with an appropriate Board Certification by the ACVP, ECVP or an eligible person. A PhD in a related field is desirable. The ideal candidate will possess complex problem-solving, data analysis and investigative skills. Strong scientific acumen and excellent verbal and written communications skills are essential to this role. Broad Experience as a study pathologist in a GLP-compliant environment within the CRO industry is an asset.

RCC offer

We offer good terms of employment, a flexible working time model and excellent social contributions in a modern and professional organization and an international environment.

Application

If you are interested, please submit your complete application documents, by February 31, 2008, the latest, to RCC Ltd, Ref. 2-861, Human Resources Zelgliweg 1, 4452 Itingen / Switzerland, hr2@rcc.ch.

Posted December 21, 2007
Application Scientist
Aperio Technologies, San Diego, CA

The Company
Aperio is digitizing pathology. We provide systems and services for digital pathology, which is a digital environment for the management and interpretation of pathology information, originating with a digital slide. Aperio serves pathologists and other professionals practicing in clinical, preclinical, research and education settings. Our award-winning ScanScope® Scanners and Spectrum digital pathology information management software improve the efficiency and quality of pathology services.

Summary:
Aperio has a wide portfolio of new algorithms that open up exciting opportunities for novel scientific workflows in the field of pathology and research in many disease areas. We seek a talented Application Scientist who will have direct involvement with pharmaceutical companies and academic medical centers in the implementation of digital pathology. This person has a unique opportunity to apply leading edge new approaches to whole slide images, working closely with customers and Aperio’s software development team.

Major Responsibilities:

• Represent Aperio’s technological and scientific excellence through strong interaction with prospects and customers
• Work closely with leading researchers at pharmaceutical companies, contract research organizations, and academic medical centers
• Present new science applications at customer sites, user-groups, trade shows, and scientific conferences.
• Match Aperio’s whole-slide scanners, web-based data management, reporting and algorithm software to the needs of customers in toxicologic pathology and clinical trials pathology.
• Help define requirements and written biology application notes for new algorithms in semi-quantiative protein expression, tissue pattern recognition, and morphology in a wide variety of disease research areas, toxicologic pathology, and clinical pathology.

Qualifications:

• Excellent written skills and interest in collaborating in research projects with customers and partners
• Outstanding oral presentation skills
• Interest in learning new computer algorithms and creativity in applying them to biological problems in a wide range of disease areas.

Requirements:

• A Ph.D. in pathology, virology, pharmacology, molecular biology or related field is highly desired. An M.S. with very strong science experience and demonstrated speaking and writing skills would also be considered.
• Interest/experience in toxicologic or veterinary pathology
• Ability to travel 50%.
• Strong abilities and interest in one or more areas of computational biology.

Location and type:
Full-time employment, from a home office, preferably near the East Coast of the United States.

Please send resume, including job code, to:
Steven J. Potts, Director, Biotech and Pharmaceutical Industry
E-mail: spotts@aperio.com

Posted December 20, 2007
Staff Pathologist
WIL Research Laboratories, LLC, Ashland, OH

If you are an accomplished Toxicological Pathologist and enjoy diverse and interesting projects, investigate the opportunities at WIL Research Laboratories, LLC. WIL Research, the fastest growing nonclinical contract research organization in the United States, is currently seeking qualified professionals in the discipline of pathology.

Staff Pathologist: Candidates are expected to have a DVM/VMD degree, or equivalent training, with in-depth training in anatomic pathology. An advanced degree in pathology (Ph.D. or M.S.) is desirable but is not absolutely required. Board certification by the American College of Veterinary Pathologists and experience in a GLP environment is preferred. However, a well-qualified Diplomate of the ACVP with no previous experience in a GLP environment would be considered, as would a Board eligible individual with appropriate GLP experience. The primary responsibility is to serve as study pathologist on safety assessment studies. Duties include review of research protocols, consultation with client representatives, gross and microscopic examinations, evaluation and reporting of results of laboratory studies conducted under GLP regulations, and interaction with clinical veterinarians. The successful candidate would be expected to work closely with toxicologists and other professionals in a friendly and relaxed team environment in the conduct of nonclinical safety assessment projects. Professional development is extremely important to WIL Research and therefore we support the attendance at two major scientific meetings per year and professional dues. Candidates will also have the opportunity for consultation with our current staff which includes 14 board certified pathologists.

WIL Research offers a competitive salary, incentive program and benefits. WIL is located in Ashland, Ohio, a pleasant mid-western town that offers a small town or rural lifestyle with a very attractive cost of living, yet boasts a local university with the associated amenities. Ashland is located in North-central Ohio, with easy accessibility to the cultural and recreational activities of Columbus, Cleveland and Lake Erie. For consideration, download an employment application from our website (www.wilresearch.com) and mail or fax to: WIL Research Laboratories, LLC, Attn: Human Resources, 1407 George Rd., Ashland, OH 44805. Fax: (419) 289-3650. EOE.

Posted December 13, 2007
Research Veterinary Pathologist
Pfizer Global Research & Development (PGRD), St. Louis, MO
Reference Req. #70469

When does research become answers?

Touching the lives of millions of people everywhere. Reaching beyond the ordinary to make an impact on something greater than the bottom line. Playing a key role in some of the most critical issues facing healthcare today.

We are Pfizer Global Research & Development (PGRD), the largest pharmaceutical R&D organization in the world. As Pfizer’s visionary discovery and development division, innovation shapes our strategy, defines our purpose and governs every facet of our operations - from the research and development that leads to pharmaceutical breakthroughs to the way we respond to the changing marketplace.

Our emphasis on innovation has enabled us to bring to market a wide range of outstanding medicines, such as Lipitor, Zithromax, Viracept, Zoloft, Viagra and our newest smoking cessation medicine, Chantix. But we recognize that there is much, much more work to be done, and we look forward to conquering the challenges facing global healthcare. Today, our research pipeline spans many therapeutic areas and research projects and we’re committed to bringing even more miracles to the marketplace. Here, we imagine that our world can be a healthier and happier place for all.

We Currently Have The Following Opportunity:

Research Veterinary Pathologist

The successful candidate will provide investigative pathology and toxicology leadership for drug discovery teams which focus on characterizing the safety of novel therapeutic targets, and discovering and developing new chemical or biologic entities intended to modulate those targets. The individual will be expected to provide a leadership role in the application and development of investigative pathology tools with an expectation of mentoring staff in the development of these tools. The individual will provide pathology support for characterization of animal models and provide guidance on interpreting their relevance to human disease.

The investigative pathology laboratory lead position requires experience working in a matrixed multidisciplinary environment and a working knowledge of the drug discovery and development process. The successful candidate will be expected to provide strategic direction for the lab, develop and foster relationships within Drug Discovery and the Global DSRD organizations and participate on local and global leadership teams.

A DVM or equivalent, PhD, or equivalent experience in research is required. ACVP or ECVP Board-certification is desirable. The individual should have strong technical knowledge and practical experienced in specialized pathology techniques such as: immunohistochemistry, in-situ hybridization, laser capture microdissection and image analysis. A working knowledge of molecular and cell biology techniques is also desirable. The St. Louis site has an emphasis on inflammation and immunology related diseases so a strong fundamental knowledge in this area would be advantageous.

Job Requisition #: 70469, St. Louis, MO

To learn more about our people, our products, and our plans for the future, visit www.pfizer.com/careers.

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Posted December 4, 2007
Assistant/Associate Professor, Veterinary Anatomic Pathology
School of Veterinary Medicine, University of California, Davis, California

Assistant/Associate Professor of Veterinary Anatomic Pathology (tenure track). School of Veterinary Medicine, University of California, Davis. Veterinarian with advanced training in anatomic pathology required. Eligibility for certification by the American College of Veterinary Pathology required. Board certification preferred. Clinical experience and competence in anatomic pathology. Demonstrated aptitude/experience in teaching. Documented research record or potential to develop an independent research program using contemporary technologies for the characterization of pathogenesis of disease at a cellular and/or molecular level is essential. Experience and expertise in the characterization of infectious disease preferred. Must possess excellent interpersonal and communication skills and a demonstrated ability to work with others in a collegial team atmosphere. To receive fullest consideration, applications must be received by February 2, 2008; position opened until filled. Expanded position description at http://www.vetmed.ucdavis.edu/pmi/PMIpage1.htm.

Interested applicants should submit 1) a letter of intent outlining special interest in the position, overall related qualifications and experience and career goals; 2) curriculum vitae; and 3) the names and addresses of three professional references to: Dennis W. Wilson, Chairman, Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, Attn: Donna Roggenkamp. AA/EOE

Posted November 29, 2007
Associate Director, CMHD Pathology Core
Toronto Centre for Phenogenomics (TCP), Toronto, Canada

TORONTO CENTRE FOR PHENOGENOMICS (TCP)

The TCP is a new state-of-the-art research centre enabling groundbreaking research and discovery, with the goal of advancing human health.

We are the largest Centre in Canada, brought about through an innovative scientific collaboration among four pre-eminent research hospitals: Mount Sinai Hospital, St. Michael’s Hospital, the Hospital for Sick Children, and the University Health Network (representing Toronto General Hospital, Toronto Western Hospital, and Princess Margaret Hospital).

The TCP is a Canadian resource, globally acclaimed, that serves researchers throughout the world. Located in the heart of Toronto’s Discovery District, the TCP pools functional expertise and resources under one roof, all to enable the best science, supported by the best infrastructure. Our ability to generate, hold, analyze, archive and distribute a critical mass of genetically engineered mice is unique. We offer 110,000 gross sq ft of customized space on four occupied and two service floors with specialized laboratories for mouse production and analysis. Our scientific staff has expertise in mouse generation, breeding & maintenance, phenotyping, pathology and cryopreservation. We also house three world-class Hospital-based Research Programs: The Centre for Modeling Human Disease (CMHD); the Canadian Mouse Mutant Repository (CMMR); and the Mouse Imaging Centre (MICe).

TCP has an immediate need for an Associate Director, CMHD Pathology Core. This challenging, newly created, leadership position reports to the Director of the CMHD Pathology Core (www.cmhd.ca) at the Toronto Centre for Phenogenomics. The Pathology Core provides extensive technical and scientific expertise to support the pathology requirements of scientists at the TCP and from around the world. You would provide expert gross-, histo-, and molecular pathology support to screen for disease or phenotypes in mice (and other species) that can be related to human disease conditions.

This position provides a unique opportunity for collaboration and intellectually-engaging collaboration across a number of disease areas, Research Institutions and academic partners in Toronto and around the world. The successful candidate should be eligible for an academic appointment with the University of Toronto and the Research Institutes of The Hospital for Sick Children and Mount Sinai Hospital.

Candidates must have a DVM degree with completion of a formal post-graduate training program in Laboratory Animal Pathology or equivalent training and/or experience in veterinary pathology. An interest or sub-specialty training in pathology of the mouse is an asset as is ACVP board certification or eligibility.

All interested candidates should email their resumes or curriculum vitae along with a cover letter before 7 December 2007 to:

HR@phenogenomics.ca
No phone calls please.
www.phenogenomics.ca

TCP thanks you in advance for your interest.
Only those applicants selected for an interview will be contacted.
In accordance with hospital policy, employment at TCP would be conditional upon satisfactory documentation of tuberculosis testing and immunization status.
TCP is an Equal Opportunity Employer.

Posted November 21, 2007
Director, Pathology
F. Hoffmann-La Roche, Basel, Switzerland

F. Hoffman-La Roche Ltd, has an opening for Director of Pathology in Non-Clinical Safety.

A pathologist in this position will provide leadership, scientific guidance and anatomic pathology support for basic research and preclinical safety projects in several therapeutic disciplines including central nervous system, and metabolic diseases. Both small molecule and therapeutic protein programs are supported. This individual will be leading a team of experienced pathologists and technical staff. The candidate will coordinate all internal pathology activities to support toxicological/non-clinical safety evaluations of development compounds, and externally with contract laboratories, consultants, and development partners. As a senior member of the global Non-Clinical Safety (NCS) organization the Head of Pathology, Basel will also collaborate with the US based Pathology groups in Nutley, NJ and Palo Alto, CA and will contribute to the overall pathology capabilities throughout the entire research organization.

Position requirements include DVM/VMD and an advanced degree MS/PhD, as well as board certification in veterinary pathology (ACVP, ECVP, German board, Swiss board or equivalent). A minimum of ten years experience in toxicologic pathology and drug development in a GLP environment, with a demonstrated ability to make sound scientific interpretations and assessments of pathology data and its relevance to human safety are required. A proven ability in leading a team of senior pathologists and technical staff are essential. Excellent interpersonal, written and verbal communication skills in English and an ability to work in a team environment are essential.

This position will be located at the F. Hoffman-La Roche facilities in Basel, Switzerland, a comprehensive drug discovery and development site in close proximity to universities and recreational facilities. Hoffman-La Roche offers a competitive salary and benefits package, as well as an excellent relocation program.

Interested in this challenging position? Please forward your application, with full supporting documentation to our personnel department: Klaus Friedrich, F. Hoffmann-La Roche Ltd, P.O. Box, CH-4070 Basel, Switzerland.

Posted November 15, 2007
Research Pathologist
Pfizer Global Research & Development (PGRD), South San Francisco, CA
Reference Req. #75044

When does research become answers?

Touching the lives of millions of people everywhere. Playing a key role in some of the most critical issues facing healthcare today.

We are Pfizer Global Research & Development (PGRD), the largest pharmaceutical R&D organization in the world.

We Currently Have The Following Opportunity:

Research Veterinary Pathologist (R7-R8)

The Research Pathologist will support project teams through scientific contributor or as an active team member, serve as a DSRD resource for advising project teams on non clinical safety packages for their programs, assist in the scientific and portfolio management of non clinical safety issues within the portfolio, advise colleagues on pathology and other investigative lab capabilities that are available in global DSRD or are identified externally, aid in the implementation of DKTP, and assist by taking on additional responsibilities or tasks, as delegated.

The Pathologist will also provide leadership as an investigative pathologist in effectively interacting with partners in site-based therapeutic areas (working with biologics). In the future, he/she may be involved in the recruitment and development and retention of staff. He/she may also develop and manage laboratory capability (initially sourced through global DSRD or outsourced) aimed at identifying and assessing tissue based Confidence in Safety (CIS), Confidence in Rationale (CIR), and target expression and safety, as well as contribute to the mechanistic understanding of target organ toxicities. The Pathologist will facilitate the effective transitions between Research and DSRD preclinical safety assessment by collaborating across the drug safety organization (General Tox, Pathology, Investigative Toxicology, DSRD CoEs, global networks, etc.), partner lines, and research to ensure that safety issues identified during Idea to LD stages are addressed prior to CAN nomination. He/she will also develop CIS strategy options for a given MOA/Target, co-author or review the DSRD contributions to the Target Knowledge Review authored by the DSRD Target Safety Lead, and develop the target safety de-risking strategy and estimate reagents and tools needed to execute the strategy Design, interpreting and communicating studies (IVTs, investigative, or mechanistic) to build CIR and CIS of targets and therapeutics, possibly including the development of new assays, biomarkers, specialized pathology techniques or molecular pathology endpoints, will also be a responsibility.

A DVM or equivalent; substantial experience in research; ACVP or ECVP Board-eligibility is required, while an ACVP or ECVP Board-certification or PhD is desired. Also necessary is experience in Investigative Pathology commensurate with role: 7-12 years of relevant experience; considerable experience leading an investigative pathology laboratory; strong background supervising pathology scientists in line or matrix role; knowledge and experience in toxicologic pathology / drug development; some knowledge of multiple scientific disciplines within safety sciences (e.g. general toxicology, safety pharmacology, genetic toxicology, and developmental/reproductive toxicology) as well as knowledge of regulatory requirements. Candidates must have a strong technical knowledge in specialized pathology techniques such as: immunohistochemistry, in situ hybridization, and laser capture microdissection.

Job Requisition #: 75044, South San Francisco, CA

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