Program

Toxicologic Pathology and the Immune System

Scientific Co-Chairs:
Susan A. Elmore, DVM, MS, DACVP, DABT, National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC
Patrick J. Haley, DVM, PhD, DACVP, Incyte Corporation, Wilmington, DE
Jerrold M. Ward, DVM, PhD, DACVP, Global VetPathology, Montgomery Village, MD

Program Agenda

The Society of Toxicologic Pathology (STP) will host a symposium on the fundamentals and recent innovations in the field of toxicologic pathology and the immune system. The focus of this international meeting is to correlate advances in the morphologic evaluation and interpretation of immunopathology findings with functional, cellular, and molecular knowledge in a series of plenary and poster sessions.

The major goal of the meeting is to provide an interactive program that allows for discussion of the current state of knowledge of immunopathology evaluations in conventional toxicology and specialized immunopathology studies. Foundational sessions will include fundamentals of Immune System Biology, including Basic Immunology, Functional Tests and Toxicologic Immunopathology; Innate Immunity; Acquired Immunity; Developmental Immunology; Challenges of Therapeutic Immunomodulation; and Issues and Observations Concerning Environmental Exposure to Immunotoxicants.

The presentations will focus on a mix of standardized and contemporary pathology methods for immunopathology investigations. The meeting will also provide a unique forum to review the progress in the application of best practices for routine and specialized pathology evaluations of the immune system across the pharmaceutical, chemical, and academic worlds of pathology. An interactive panel discussion will explore the issues associated with differentiation ofstress effects and immunotoxicity.

The traditional NTP Satellite Symposium, entitled Pathology Potpourri, in advance of the symposium will focus on the customary presentations of challenging lesions but will also include a presentation on proposed INHAND lymphoid nomenclature. Four continuing education sessions will be held on Sunday before the general sessions begin; Interacting with Regulatory Authorities: What to Do and What Not to Do; Biomarker Discovery, Qualification, and Application in Drug Development: What’s New, and What You Need to Know; Ultrastructural Analysis and Toxicologic Pathology; and Histopathology of the Rodent Lymphoid and Hematopoietic Systems. A half-day Career Development Workshop: “Leaving the Rat Race: Consulting As a Career Choice in Toxicologic Pathology” will also be held on Sunday and the Career Development Lunchtime Series Monday will provide guidance on the use of professional networking in career development.

The immune system and its responses is one of the more complex and challenging arenas of toxicologic inquiry and regulatory concern, and this congress promises to be an opportunity to review and expand your knowledge in this important field. We hope you will join us for this exciting program in Denver.