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General Information Scientific Program Exhibits Hotel & Travel Registration Abstracts Students      

 

Abstract Submission
Deadline

April 1, 2014

Student Travel Award
Deadline

April 1, 2014

Advance Registration
Deadline

April 10, 2014

Preregistration
Deadline

May 20, 2014

Meeting Cancellation
Deadline

May 10, 2014

Hotel Reservation
Deadline

May 22, 2014

General Information

TRANSLATIONAL PATHOLOGY: Relevance of Toxicologic Pathology to Human Health

Scientific Co-Chairs: Sabine Francke, DVM, PhD, FIATP, US FDA/CFSAN; Mark Hoenerhoff, DVM, PhD, DACVP, NIEHS; and Lee Silverman, DVM, PhD, DACVP, Agios Pharmaceuticals

Toxicologic pathologists work in diverse settings studying changes elicited by pharmacological, chemical, and environmental agents, and factors that modify these responses. This work involves the integration of pathology data into hazard identification, risk assessment, and risk communication frameworks that guide safety decisions for potentially toxic substances. A central part of this process is the translation of pathologic effects in animal models to address specific issues in public health.

This symposium will focus on translational science and the relevance of toxicologic pathology to human health. Topics will include the predictive value of nonclinical models and how animal model and human endpoints inform each other. Progress in the development of new nonclinical animal models and other types of models will be discussed, highlighting areas where models are highly predictive of human endpoints and areas where alternative models are needed. Emerging technologies which have the potential to improve translational capabilities will also be presented, with an emphasis on advancements that will impact regulatory decision making in coming years. As the field of epigenetics is rapidly advancing, the role and utility of epigenetic endpoints in toxicologic pathology and their relevance to human health will be addressed. Environmental toxicologic pathology plays a critical role in understanding health impacts of environmental exposures; therefore, how pathology outcomes inform human health assessments and regulatory decisions will be discussed. Finally, as the incidence of comorbidities in the human population increases, there is a greater need to develop translational models that provide useful information on human populations with comorbidities; the challenges of developing such relevant animal models will be addressed. By the end of this symposium, the audience will have a better understanding of current trends and data needs in translational pathology and how the field of toxicologic pathology can leverage expertise and tools to meet these needs.

US Government Employee Tuesday-Only Sessions Registration
The scientific sessions on Tuesday, June 24, have been designed in response to requests from the Federal regulatory community. Interested US Government employees may register to attend Tuesday morning and afternoon sessions listed below at no charge (Full meeting attendees also may attend at no charge). Registration (indicating one or both sessions) is required by June 1.

  • Tuesday AM Scientific Session: Emerging Technologies
  • Tuesday PM Scientific Session: The Role of the Toxicologic Pathologist in Informing Regulatory Decisions and Guiding the Interpretation and Application of Data from New Technologies and Tools

Annual Symposium Overview

Preliminary Program

Online Registration

Saturday, June 21
Pre-Meeting NTP Symposium: Pathology Potpourri—Free Event, Registration Required

Sunday, June 22
CE Courses (half-day, fee to attend)

  • Biomarkers of Endocrine Effects and Reproductive Toxicity
  • Scientific and Regulatory Considerations In the Safety Evaluation of Stem-Cell Derived Therapies in Preclinical Studies
  • Fundamentals of Translational Neuroscience in Toxicologic Pathology: Optimizing the Value of Animal Data for Human Risk Assessment
  • The Art of Study Monitoring and Pathology Peer Review: How to Maintain a Relationship of Mutual Respect with CRO’s

Career Development Workshop: Effective Communication of Pathology Results in Regulatory Studies (AM half day)—Free Event, Registration Required

Welcome Reception/Exhibits Opening

Monday, June 23
Exhibits and Poster Sessions Open

Symposium Welcome

Session 1
(AM): Toxicity Concordance from Animals to Humans: How Predictive Are Traditional Preclinical Studies of Adverse Effects or Toxicities in Clinical Studies?

Career Development Lunchtime Series: Draft OECD Guidance on the GLP Requirements for Peer Review of Histopathology: A Panel Discussion (Free Event, Registration Required)

Session 2 (PM): Progress in Preclinical Testing for Translational Science

Town Hall Meeting

Tuesday, June 24
Exhibits and Poster Sessions Open

Session 3 (AM): Emerging Technologies

Exhibitor-Sponsored Lunch for Symposium Registrants (Full Meeting and Tuesday-Only Attendees)

Session 4 (PM): The Role of the Toxicologic Pathologist in Informing Regulatory Decisions and Guiding the Interpretation and Application of Data from New Technologies and Tools

Student Outing

Wednesday, June 25
Exhibits and Poster Sessions Open

Excel Tips and Tricks: Easy Ways to Quickly Visualize Your Pathology Data
(12:00 Noon–1:30 PM) (Free Event, advance registration required)
Sponsored by IATP and STP
Session Details

Session 5 (AM): Epigenetic Endpoints in Toxicologic Pathology and Relevance to Human Health

Session 6 (PM): Environmental Toxicologic Pathology and Prediction of Human Health Risks

Awards Ceremony
Annual Business Meeting
President’s Reception

Thursday, June 26
Session 7 (AM): The Challenges of Safety Evaluation in Populations with Concurrent Disease

Meeting Materials

Meeting publications, including final Program, handouts, attendee list, committee, interest group, and ancillary meetings schedules and evaluation forms will be posted on the Meeting Materials page when available. All STP Members and also nonmember registrants will be notified when materials are posted.

STP members will use their regular logins to access this page. Nonmember attendees will receive logins and passwords to access this page.

Accessibility for Persons with Disabilities

STP wants to ensure that no individual with a disability is excluded, denied services, segregated or otherwise treated differently than other individuals because of the absence of auxiliary aids and services. If you need any auxiliary aids or services identified in the Americans with Disabilities Act, or any assistance in registering for this meeting, please contact STP Headquarters, 703-438-7508, ext. 1443.

Annual Symposium Policies

Child Attendance Policy

Photography, Videotaping, Recording Policies
Photography of poster presentations is prohibited without the specific consent of the presenter(s)/author(s). Photography of exhibitor booths and/or equipment is prohibited without the specific consent of the exhibitor. Photography, Videotaping, or Recording of Scientific Sessions or CE Courses is not permitted.

Sponsors

STP wishes to thank its Corporate Sponsors for their generous support of the Society and its activities, which include all events and scientific sessions at the Annual Meeting. Their donations make it possible for STP to continue to offer high quality science at an affordable fee.

2014 Sponsors

Sponsorship Opportunities


Technical Support
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