Program

Mechanisms of Toxicity

Program Agenda

The global regulatory agencies and the general public require outstanding scientific rigor and quality in the human risk assessment of xenobiotics. To meet these demands, the toxicology and pathology professions are positioned to take advantage of key learnings captured from major advances in the molecular understanding of host defense, disease, and toxicity processes. The purpose of the 2012 Annual Symposium of the Society of Toxicologic Pathology will be to examine mechanisms of toxicity in six general sessions covering tissue injury related to the following: 1) host factors, 2) chemical structure, 3) xenobiotic cellular targets (on- and off-target), 4) new technologies (e.g., nanotechnology, siRNA therapy and immunoconjugates), 5) cellular organelle specific effects, and 6) high-profile environmental chemicals and consumer products.

Five continuing education sessions will be held on Sunday before the general sessions begin including: 1) Mechanism-Based Approaches to Cardiovascular Safety Assessment, 2) Nontraditional Applications of Clinical Pathology in Drug Discovery and Preclinical Toxicology,  3) The ACT-Sponsored: Drug Development 101 course, 4) The Placenta As an “Immune Organ” and Its Relevance in Toxicological Studies and 5) A half-day Career Development Workshop: Presentation Skills and Scientific Advocacy.

A Career Development Lunchtime Series held on Monday will provide participants guidance on careers in environmental toxicology.