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Amgen, South San Francisco, Cambridge (MA), Thousand Oaks, or Remote—Pathologist Associate Director

Posted:
Company: Amgen
Location: South San Francisco, Cambridge (MA), Thousand Oaks, or Remote
Job Title: Pathologist Associate Director

Position Description:

In this vital role in Translational Safety and Bioanalytical Sciences, you will contribute to the drug development process from target identification and validation through product registration, including interpretation and integration of complex nonclinical pathology datasets and providing context for human risk assessment.

Key Responsibilities:

  • Demonstration of specialized pathology expertise and contribution to a specific scientific area.
  • Provide pathology guidance in the resolution of issues within the function / department..
  • Interpret and integrate complex pathology datasets.
  • Problem-solve nonclinical safety issues.
  • Guide the successful completion of multiple programs in a project leadership role (e.g., project pathologist) or as the lead scientific / technological resource.
  • Communicate and presents scientific information formally and informally within area of expertise to a diverse set of audiences, including senior management and the external professional and scientific community.

Basic Qualifications:

  • DVM and 4+ years of relevant pathology and research experience
  • Diplomate of the ACVP (or equivalent)
  • Broad knowledge of leading and / or state of the art principles and theories in discipline and basic knowledge of related and adjacent disciplinary areas
  • Understands broader organizational goals and business priorities in relation to therapeutic program / work group
  • Preferred Qualifications:

    • Demonstration of specialized pathology expertise and contribution to a specific scientific area.
    • Provide pathology guidance in the resolution of issues within the function / department..
    • Interpret and integrate complex pathology datasets.
    • Problem-solve nonclinical safety issues.
    • Guide the successful completion of multiple programs in a project leadership role (e.g., project pathologist) or as the lead scientific / technological resource.
    • Communicate and presents scientific information formally and informally within area of expertise to a diverse set of audiences, including senior management and the external professional and scientific community.

    What you can expect of us

    As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

    Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

    • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
    • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
    • Stock-based long-term incentives
    • Award-winning time-off plans and bi-annual company-wide shutdowns
    • Flexible work models, including remote work arrangements, where possible
    • Link to Apply: https://careers.amgen.com/en/job/south-san-francisco/pathologist-associate-director/87/60953632688

The Laboratory of Comparative Pathology (LCP) of Memorial Sloan Kettering Cancer Center, New York, New York, United States—Fellowship in Comparative and Genomic Pathology

Posted:
Company: The Laboratory of Comparative Pathology (LCP) of Memorial Sloan Kettering Cancer Center
Location: New York, New York, United States
Job Title: Fellowship in Comparative and Genomic Pathology

Position Description:

The Laboratory of Comparative Pathology (LCP) of Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, Hospital for Special Surgery, and The Rockefeller University is accepting applications for a 15-month postdoctoral fellowship in comparative and genomic pathology for veterinary pathology trainees seeking to advance their knowledge in these disciplines.

The fellow takes advantage of a large and diverse laboratory animal caseload and state-of-the-art facilities housed within the LCP, providing capacity for necropsy, histology, immunohistochemistry, in situ hybridization, whole slide digital image analysis, hematology, clinical chemistry, microbiology, parasitology, and serology. Other core facilities housed within the institutions provide access to in vivo imaging, transmission and scanning electron microscopy, confocal microscopy, and laser capture microdissection equipment and expertise.

Responsibilities include performing gross pathologic and histopathologic examinations of a variety of laboratory animal species (mice, rats, hamsters, rabbits, guinea pigs, pigs, non-human primates, fish, amphibians), interpreting findings, preparing reports, and communicating with clinical veterinarians and research personnel. Scientific collaborations and publications are encouraged. Supervision by 3 boardcertified pathologists (ACVP and/or ECVP) is provided. The fellow participates in didactic activities held jointly with the Tri-Institutional Training Program in Laboratory Animal Medicine & Science, including Histopathology and Gross Pathology Rounds, Clinical and Pathology Conference, Laboratory Animal Medicine Seminar Series, and Journal Club.

Applicants must possess a DVM/VMD from an AVMA-accredited or equivalent institution and have completed at least 2 years of residency anatomic pathology training. Preference will be given to candidate who have completed 3 years of anatomic veterinary pathology training. Salary is based on the NIH postdoctoral scale and commensurate with experience. The start date is on October 1st of each year, and the application deadline is February 28, 2024.

Applicants should submit a Letter of Intent specifying interests and professional goals, curriculum vitae, veterinary education transcripts, and three letters of recommendation. Application materials and questions should be addressed to:

Sebastián Carrasco DVM, MPVM, MSc, PhD, Dipl. ACVP
Laboratory of Comparative Pathology
Center of Comparative Medicine and Pathology
Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine
1275 York Avenue, Box 270, New York, NY 10065
CarrascS@mskcc.org

Toxicologic Pathology Associates (TPA), Inc., Jefferson (Little Rock Metro area), Arkansas, United States—Veterinary Anatomic Pathologist (Onsite with remote-work flexibility)

Posted:
Company: Toxicologic Pathology Associates (TPA), Inc.
Location: Jefferson (Little Rock Metro area), Arkansas, United States
Job Title: Veterinary Anatomic Pathologist (Onsite with remote-work flexibility)

Position Description:

TPA is looking for a research-oriented, veterinary anatomic pathologist to join our team at the National Center for Toxicological Research (NCTR) in Jefferson, Arkansas, which is the only Food and Drug Administration (FDA) research center located outside the Washington D.C. metropolitan area. The one-million square foot research campus in Jefferson plays a critical role in the research and regulatory missions of the FDA and the Department of Health and Human Services (HHS) to promote and protect public health.

TPA is an employee-owned contract research company supporting the broad investigative pathology needs of the NCTR’s research program. Many of our staff members have worked in close collaboration with the Federal investigators as key participants of high-profile Inter-Agency (IAG) research programs for several decades. TPA provides routine toxicologic pathology services involving examination of tissues from standard toxicology studies and a wide-variety of investigative pathology-based technologies geared to meet specific research objectives. The successful candidate as a key staff member, will routinely collaborate with the NCTR investigators to support their research activities.

Historically, the NCTR has been a critical part of several Interagency Research Agreements (IAGs) including an IAG that combines the investigative resources of both the FDA/NCTR and the NIEHS’s National Toxicology Program (NTP). The unique aspect of this agreement facilitates interactions between internationally recognized FDA and NTP investigators and their research programs for which TPA provides the collaborative pathology services.

Essential Responsibilities:

  • Collaborate with the NCTR researchers for the development of study protocols.
  • Oversee methods development and necropsies involving a wide variety of laboratory animals and provide scientific guidance to necropsy technicians to ensure accuracy and compliance with protocols and Standard Operating Procedures (SOPs).
  • Perform microscopic evaluation of tissues on GLP/non-GLP studies and correlate findings with necropsy, organ weight and other pathology findings.
  • Provide pathology support in the interpretation of chemical or drug-related toxicology findings.
  • Author comprehensive pathology narrative reports detailing all gross and microscopic findings while meeting report deadlines.
  • Serve as a peer review pathologist and/or participate in pathology working groups (PWGs).
  • Collaborate on the preparation of publications and perform scientific review of manuscripts.
  • Work directly with Investigative Researchers to ensure client satisfaction.

Minimum requirements:

  • DVM/VMD degree or equivalent and Board-certification by the American College of Veterinary Pathologists. For non-board-certified individuals, about 5 years of experience in toxicologic pathology is required.
  • PhD (or equivalent) preferred but significant investigative and/or industry experience in toxicologic pathology or a related discipline also considered.
  • Hands-On Training/Experience in pathology-based specialty areas such as molecular pathology, immunohistochemistry, in situ hybridization, organ on a chip technology, digital image analysis is desirable.
  • Experience working under GLP guidelines is desirable.
  • Eligibility to work in the United States.
  • Ability to work independently as well as having demonstrated collaborative skills.

How to Apply / Contact

TPA is an equal opportunity employer. We do not unlawfully discriminate against any applicant because of race, sex, gender, ethnicity, religion, creed, age, color, military/veteran status, genetic condition or information, sexual orientation, gender identity, national origin, ancestry, marital status, qualified physical or mental disability, transgender status, or any other legally protected class in accordance with federal, state and local laws.

TPA provides a competitive starting salary commensurate with applicant’s qualifications, expertise, and experience. TPA also offers a comprehensive benefits package which includes salary, medical, dental, employer paid long-term and short-term disability, 401K with company match and paid time off. The position is on-site with remote-work flexibility. The selected candidate will also be eligible for key-personnel bonus program.

Employment of successful candidate will be contingent upon the receipt of a satisfactory drug screening report and obtaining the necessary government clearance. Interested candidates should submit their application, resume and contact information to kimberly.maynard@fda.hhs.gov

If you have any questions about this position, please contact:

Dr. Pritpal S. Malhi DVM, PhD, DACVP
President and Program Director
pritpal.malhi@fda.hhs.gov
870-543-7404

For additional information about TPA, please visit our website at www.TPAInc.biz

Charles River Laboratories, US Remote—Sr. Veterinary Pathologist

Posted:
Company: Charles River Laboratories
Location: US Remote
Job Title: Sr. Veterinary Pathologist

At Charles River, we are passionate about improving the quality of people’s lives. When you join our global family, you will help create healthier lives for millions of patients and their families.

Charles River employees are innovative thinkers, who are dedicated to continuous learning and improvement. We will empower you with the resources you need to grow and develop in your career.

As a Charles River employee, you will be part of an industry-leading, customer-focused company at the forefront of drug development. Your skills will play a key role in bringing life-saving therapies to market faster through simpler, quicker, and more digitalized processes. Whether you are in lab operations, finance, IT, sales, or another area, when you work at Charles River, you will be the difference every day for patients across the globe.

We are seeking an experienced Senior Veterinary Pathologist. This position can be remote anywhere within the U.S.

Our Veterinary Pathologists are responsible for independently performing gross and microscopic evaluation of tissues, recording results, preparing reports delineating pathological findings, and assisting with necropsy supervision. With minimal supervision, work with customers as needed to market company services and to assure customer satisfaction.

  • Perform macroscopic and microscopic tissue evaluation and interpretation of assigned studies.
  • Assist with necropsy supervision and may conduct necropsies, including gross pathology interpretation, sample collection and fixation.
  • Enter pathology findings in data capturing system(s).
  • Write comprehensive report narratives detailing all test article effects. As needed, work with study directors to ensure data is accurately integrated into study reports.
  • May serve as a study director or principal investigator.
  • May function as a peer review pathologist or participate in a pathology working group (PWG).
  • Provide training, technical guidance and leadership to laboratory staff and provide training, guidance, and leadership to less experienced pathologists.
  • May serve as a consultant in pathology-related issues.
  • May provide scientific expertise for experimental design and other aspects of research studies as needed.

Qualifications:

  • Education: Doctoral degree (D.V.M./V.M.D.) from an accredited veterinary school, or acceptable international equivalent in veterinary medicine.
  • Experience: 5 or more years of pathology experience post-D.V.M.; working knowledge of clinical pathology; specialized training and/or experience in toxicologic pathology. 2 or more years of toxicologic pathology required.
  • Certification/Licensure: American College of Veterinary Pathologists (A.C.V.P.) board-certification required to enter the grade at the minimum experience level.
  • Other: Demonstrated success in technical proficiency, scientific creativity, collaboration with others and independent thought. Works on problems of diverse scope in which analysis of data requires evaluation of identifiable factors. Exercises judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions. Computer literacy in word processing, spreadsheet and database software.

Apply Online!

Charles River Laboratories, Mattawan, MI—Clinical Pathologist II

Posted:
Company: Charles River Laboratories
Location: Mattawan, MI
Job Title: Clinical Pathologist II

Position Description:

A Clinical Pathologist 2 is responsible for all aspects of clinical pathology conducted on research studies. Partner with Study Directors to provide comprehensive interpretation and preparation of the clinical pathology portions of reports. Participate in protocol development, and give scientific input to laboratory staff and clients as requested.

Essential Functions:

The fundamental Duties & Responsibilities of the role (products and services provided/results accomplished) include, but are not limited to, those listed:

  • Responsible for preparation of assigned clinical pathology reports. Work with the Study Director to accurately integrate data into the final study report.
  • Responsible for the collection and reporting of clinical pathology data in studies. Provide assistance to Study Directors in the interpretation of clinical pathology endpoints.
  • Serve as Study Clinical Pathologist, Study Director, or Principal Investigator on studies, as assigned, within the Clinical Pathology department.
  • Interact with Anatomic/Veterinary Pathologists to ensure relevant and appropriate correlations for clinical and anatomical pathology endpoints.
  • Evaluate study specimens related to clinical pathology, such as blood smears, bone marrow smears, urinalysis sediment preparations, and body fluid preparations. Evaluate other materials as necessary and appropriate.
  • Provide scientific expertise for experimental design and conduct of research studies. Participate in method development and identification and evaluation of new instrumentation as required. Assist in expanding the array of clinical pathology assays to meet contemporary needs and expectations.
  • Conduct on-site employee training in clinical pathology or related topics as needed for studies, specialty projects, or continuing education.
  • Provide expertise and guidance to Clinical Pathology personnel with technical issues.
  • Review and approve new/revised Standard Operating Procedures (SOPs) pertaining to pathology. Confirm department SOPs are developed and maintained according to established guidelines.

Job Qualifications:

Qualifications (Knowledge, Experience, Skills and Abilities required to accomplish the essential functions) include but are not limited to:

  • D.V.M. / V.M.D. (Doctor of Veterinary Medicine) degree required. Ph.D. in Clinical Pathology or related discipline preferred, with minimum 5 years of related experience in clinical pathology or experimental pathology.
  • Board certification by the American College of Veterinary Pathologists (D.A.C.V.P.) with specialty in Clinical Pathology required.
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Demonstrated leadership skills as they pertain to intra- and interdepartmental initiatives, Sponsor interactions, and business development.
  • Ability to communicate verbally and in writing at all levels inside and outside the organization.
  • Basic familiarity with Microsoft Office Suite.
  • Computer skills, commensurate with Essential Functions, including the ability to learn a validated system.
  • Ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts, sometimes on short notice.
  • Ability to work under specific time constraints.

Link to Apply: https://jobs.criver.com/job-invite/221338/

Genmab, Princeton, NJ—Associate Director, Pathology

Posted:
Company: Genmab
Location: Princeton, NJ
Job Title: Associate Director, Pathology

At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in science, we believe that being proudly unique, determined to be our best, and authentic is essential to fulfilling our purpose.

The Role
As a Pathologist at Genmab, you will be part of an international Pathology team embedded within Precision Medicine of our Translational and Quantitative Sciences team based in Princeton, New Jersey. In this role you will work with scientists in a state-of-the-art histology and immunohistochemistry laboratory to support a variety of discovery, pre-clinical and clinical programs.

Responsibilities
The anatomic pathologist in this role will impact Genmab’s pipeline from early research to clinical trial stages, providing expertise in histopathological evaluation, tissue-based assay development (IHC, ISH, IF), biomarker strategy and toxicologic pathology for a variety of antibody therapeutics.  Scientific curiosity, strategic thinking, and the capacity to work well in cross-functional teams are important traits of the successful candidate.

You will contribute your pathology expertise by both traditional slide evaluation, and by guiding the development and interpretation of advanced tissue-based assays, such as multiplex immunofluorescence panels, digital image analysis, and machine learning image projects.

Your responsibilities include but are not limited to the following:

  • Help laboratory personnel in our US and European locations to design and develop immunohistochemistry assays for single-plex chromogenic and fluorescence, in situ hybridization (ISH) assays, multiplex IF and ISH-IF combinations (10% lab work IHC/IF assay development).
  • Support our digital pathology team and work closely with Data Sciences to develop and verify digital image analysis algorithms and results from image analysis projects.
  • Evaluate, qualitatively and quantitatively (H-Scores, % staining, etc) a variety of immunohistochemical stains for target screening and biomarker assessment.
  • Serve as in-house expert representing Genmab in interactions with CROs developing IHC and ISH assays to support our pre-clinical and clinical biomarker programs.
  • Perform, as needed, primary reads and/or peer review of pre-clinical toxicology studies, including tissue cross reactivity studies, investigative and GLP studies.
  • Provide internal expertise to understand the mechanisms of toxicity observed non-clinically or clinically in order to help design mitigation strategies and minimize risk to patients.
  • Contribute with evaluation, and implementation of new technologies and techniques for tissue-based assays and digital image analysis applications.

Requirements

  • Doctor in Veterinary Medicine or equivalent degree, with a minimum of 2-5 years of industry experience supporting discovery and development organizations.
  • Diplomate, American College of Veterinary Pathologists (or equivalent) in anatomic pathology.
  • Graduate degree (Master’s or PhD) desired.
  • Solid experience with design and interpretation of immunohistochemistry assays and digital pathology applications.
  • Strategic thinking, innovative and collaborative mindset and a willingness to work in multidisciplinary teams.
  • Basic knowledge of statistics and data visualization software (SAS, GraphPad, Spotfire).
  • Experience managing pathology laboratories desired, but not required.
  • Background in immunology and immuno-oncology, knowledge of biomarker development and companion diagnostic development is desired but not required.

For US based candidates, the proposed salary band for this position is as follows:
$142,500.00–$237,500.00

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as bonuses.

About You

  • You are passionate about our purpose and genuinely care about our mission to transform the lives of patients through innovative cancer treatment
  • You bring rigor and excellence to all that you do. You are a fierce believer in our rooted-in-science approach to problem-solving
  • You are a generous collaborator who can work in teams with diverse backgrounds
  • You are determined to do and be your best and take pride in enabling the best work of others on the team
  • You are not afraid to grapple with the unknown and be innovative
  • You have experience working in a fast-growing, dynamic company (or a strong desire to)
  • You work hard and are not afraid to have a little fun while you do so

Locations
Genmab leverages the effectiveness of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are designed as open, community-based spaces that work to connect employees while being immersed in our state-of-the-art laboratories. Whether you’re in one of our collaboratively designed office spaces or working remotely, we thrive on connecting with each other to innovate.

About Genmab
Founded in 1999 in Copenhagen, Denmark, Genmab is an innovative biotech company that has become a leader in antibody biology and innovation. Our product pipeline and next-generation antibody technologies are the result of our strong company culture, a deep passion for innovation, and desire to transform cancer treatment and serious diseases.

When you work with us, you’ll be part of a warm, fun, dynamic community, and team up with some of the best, most authentic individuals in locations around the world, who care deeply and share in a relentless drive to innovate and create transformational medicines. People who are candid, impact-driven, and a little unconventional; who seek out and embrace the opportunity to build new and bold futures within a rapidly growing and innovative biotech company; who bring their full selves to work and show up for each other - rolling up their sleeves to get the job done. This translates into a place where you can be authentically you; are empowered to innovate, build solutions, and execute; feel cared for and supported in growth; and are a critical part of changing the lives of patients around the world through transformative cancer treatment.

Our commitment to Diversity, Equity, and Inclusion
We are committed to fostering workplace diversity at all levels of the company and we believe it is essential for our continued success. No applicant shall be discriminated against or treated unfairly because of their race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), national origin, age, disability, or genetic information. Learn more about our commitments on our website.

Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website https://www.genmab.com/privacy.

Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.

Apply Online!

Tufts University, North Grafton, MA and Cambridge, MA.- Takeda—Fellowship Program

Posted:
Company: Tufts University- Takeda
Location: North Grafton, MA and Cambridge, MA.
Job Title: Fellowship Program

Joint Tufts-Takeda Fellowship Program in Comparative Molecular Genetic Pathology and Pathology Informatics

Program Description

Applications are invited for a one-year fellowship in Comparative Molecular Genetic Pathology and Pathology Informatics. The fellow will use existing computer-aided image processing, analysis, deep-learning and artificial intelligence modalities actively applied in medical applications, biomedical research and drug safety to investigate pathogenesis-related questions for research emphasizing infectious disease including COVID-19 and/or tuberculosis, oncology, toxicologic pathology, and translational medicine. The goals of this fellowship are to: 1) Create and use digital pathology tools to understand disease pathogenesis in animal models of human disease; 2) Extract and quantify image features for quantitative analyses and predictive modelling; 3) Gain an understanding of how machine and deep learning, artificial intelligence and spatial biology apply to modern pathology and biomedical research; and, 4) Develop critical thinking, scientific communication, grant-writing skills, and an understanding of the drug development process.

The candidate will develop a research project(s) in the Comparative Pathology and Genomics Shared Resource (CPGSR) at Tufts Cummings School of Veterinary Medicine and the Integrated Digital Pathology Lab (iDigPath) at Takeda that will be supervised by Amanda Martinot, DVM, PhD, DACVP (Anatomic; Tufts) and Krista LaPerle, DVM, PhD, DACVP (Anatomic; Takeda). Takeda is a global, R&D-driven, biopharmaceutical leader committed to development of life-changing treatment for patients. The fellow will spend 6 months on the North Grafton campus at Tufts Cummings School of Veterinary Medicine and 6 months at the Takeda Boston campus in Cambridge, MA. At Tufts Cummings School, the candidate will be involved in developing and evaluating animal models of human disease for both internal and external users of the CPGSR using digital pathology (50%). At Takeda, the candidate will assist toxicologic pathologists, imaging specialists and bioinformaticians to learn how to develop and utilize complex image analysis applications to build algorithms, analyze multiplex images, and integrate spatial transcriptomics for drug safety assessments, vaccine testing, and therapeutic development (50%).

Salaryand Benefits

  • One (1) year, 1.0 FTE fixed term research fellowship (no diagnostic service) with the potential for extension
  • Stipend begins at $75,000, not to exceed $100,000, and is commensurate with experience
  • Additional benefits include attendance at one conference per year and associated health benefits
  • Tentative start date of April 1, 2024 (negotiable)

Qualifications
The candidate must have:

  • A DVM/VMD degree or equivalent, preferably from an AVMA-accredited institution
  • Completed a veterinary anatomic pathology residency and/or combined veterinary anatomic pathology residency/graduate degree program
  • Board certification or board eligibility by the American College of Veterinary Pathologists (ACVP)
  • Prior experience in biomedical research
  • Additional skills, including: excellent verbal and written communication, self-motivation, the ability to work independently and collaboratively, as well as analytically and creatively problem solve

Required Application Materials Due February 16, 2024

  • An updated CV
  • Statement of career goals including past pathology and research experiences and motivation for pursuing this position
  • Complete contact information for three (3) referees
  • Please electronically submit application materials as a single pdf to Trena Haroutunian via email

For More Information, Contact

Amanda Martinot, DVM, MPH, PhD, Dipl. ACVP (Anatomic)
E.A. Stevens Assistant Professor, Department of Infectious Diseases and Global Health Co-Director Comparative Pathology and Genomics Shared Resource
Tufts Cummings School of Veterinary Medicine
Amanda.martinot@tufts.edu
508-887-4448

Krista LaPerle, DVM, PhD, Dipl. ACVP (Anatomic)
Scientific Director, Drug Safety Research & Evaluation
Lead, Integrated Digital Pathology (iDigPath)
Takeda Pharmaceutical Company
Krista.LaPerle@Takeda.com
614-787-4639

Cornell University College of Veterinary Medicine, Ithaca, NY—Tenure Track Faculty Position in Clinical Pathology

Posted:
Company: Cornell University College of Veterinary Medicine
Location: Ithaca, NY
Job Title: Tenure Track Faculty Position in Clinical Pathology

The Department of Population Medicine and Diagnostic Sciences (PMDS) at the Cornell University College of Veterinary Medicine (CVM) invites applications for a tenure track Clinical Pathology faculty position at the Assistant, Associate, or Full Professor level. We are seeking highly motivated individuals who bring their clinical pathology expertise to the diagnosis and study of disease affecting companion, production and wild animal species.

The Clinical Pathology Laboratory is one of twelve testing units of the Animal Health Diagnostic Center (AHDC), a state-of-the-art veterinary diagnostic laboratory accredited by the American Association of Veterinary Laboratory Diagnosticians (AAVLD). The successful candidate will join three American College of Veterinary Pathologists (ACVP) board certified clinical pathologists who work collaboratively to perform their clinical, teaching, and residency training responsibilities. The Clinical Pathology Laboratory offers comprehensive hematology, chemistry, urinalysis and cytology testing to AHDC clients and to patients at the Cornell University Hospital for Animals (CUHA). This environment provides rich opportunities for collaboration with both clinicians and research investigators at the CVM, Cornell University and other institutions.

The primary responsibilities of the position will be to engage in clinical service in the Clinical Pathology Laboratory and to develop a research program in a field related to clinical pathology. The expected effort distribution for this role is 40% devoted to diagnostic service, at least 35% devoted to research, and the remainder to teaching and academic service. Research interests may include, but are not restricted to, hematology, clinical chemistry, oncology, immunology, metabolic diseases, and development of specialized/improved clinical pathology tests and/or techniques. The CVM and Cornell University have robust and wide-reaching research centers (Baker Institute for Animal Health, Dairy Center of Excellence, Feline Health Center, Riney Canine Health Center), that provide multiple opportunities for research collaboration and considerable internal funding for which the successful candidate will be eligible to apply. The position also will include commitments to the DVM-teaching and clinical pathology residency training program at the CVM. Qualified candidates must hold a DVM (or equivalent degree) and preferably a PhD in a related biomedical field, be certified by the ACVP in Clinical Pathology (or be eligible for certification) and have a record of scholarly accomplishment.

Located in Ithaca, the heart of the beautiful Finger Lakes region of Upstate New York, Cornell University is a globally recognized center for discovery, academic leadership, and service and is an exceptional place to work and study. The College of Veterinary Medicine at Cornell embraces diversity and seeks candidates who will create a climate that attracts students of all races, nationalities and genders. We seek candidates who will contribute to a collegial environment, strive for academic and service excellence, and help us to build diversity through a strong commitment to teaching and mentoring.

The salary range for this position is $120,000 to $195,000, depending on qualifications and experience. To apply, submit a cover letter including a statement of career goals, curriculum vitae, statement of research interests and plans (up to two pages), statement of teaching interests and plans (one page), and the names of three individuals who can provide references. In addition, we ask applicants for all faculty positions to share their experiences and/or approaches (past, current, or future) to fostering learning, research service, and/or outreach in a diverse community. Applicants may choose to submit a stand-alone statement or embed the information in other parts of their application materials. All materials must be submitted as PDF files at academicjobsonline.org. Review of applications will begin on January 22, 2024 and will continue until the position is filled. For more information, contact Dr. Andrew Miller, Chair of the Search Committee.

Diversity and Inclusion are a part of Cornell University's heritage. We are a recognized employer and educator valuing AA/EEO, Protected Veterans and Individuals with Disabilities. The University seeks to meet the needs of dual career couples and has a Dual Career program to assist with dual career recruitment.

The Cornell University College of Veterinary Medicine is recognized internationally as a leader in animal medicine, veterinary medical education, public health, and biomedical research.

Apply Online!

Lovelace Biomedical Research Institute, Albuquerque, NM—Pathologist

Posted:
Company: Lovelace Biomedical Research Institute
Location: Albuquerque, NM
Job Title: Pathologist

Job #: ID2023-2101
Category: Scientific Research
Type: Full-time

Overview

Lovelace Biomedical is seeking a board-certified Veterinary Pathologist to join a team of researchers dedicated to the Lovelace mission of advancing and bettering human health.

At Lovelace Biomedical, we support a bevy of exciting advanced research and development initiatives in a hybrid contract -academic environment. Our core competencies include R&D services for pharmaceutical, chemical, and agricultural industries; pharmacology models and safety assessment; inhalation toxicology; advanced chemical, biological, radiological, nuclear threat and explosive (CBRNE) and combat casualty care countermeasure (drug and vaccine) development; respiratory, cardiovascular and infectious disease research; real-world environmental hazard assessment; intellectual property development; applied imaging-bioinformatic neurocognitive research, and clinical research, etc. Our funding sources range from small pharma and biotech, to large pharma and industry to NIH, DOD, DOE, BARDA and other governmental agencies.

The Veterinary Pathologist will be part of a team with a larger scientific purpose, and the successful candidate will have the ability to see the big picture of our goals and be driven by the desire to advance our research. They will also be able to collaborate effectively with internal and external clients, have an inquisitive scientific mind and the desire to learn new and exciting disciplines.

In addition to providing technical guidance and oversight (may include supervision of laboratories and/or staff) to personnel in the necropsy, histology and clinical pathology groups, the Veterinary Pathologist will evaluate, interpret and report on microscopic changes from a variety of animal models of disease; and may serve as the principal investigator or study director on a variety of sponsored programs; supervise and oversee the development and evaluation of disease models and safety/efficacy studies; support and develop investigator-initiated sponsored research programs; and perform all other related duties as required or assigned.

Qualifications

  • Requires a Doctorate in Veterinary Medicine, or a comparable degree from an AVMA accredited program, residency training as a Veterinary Pathologist, and a minimum of 2 years of directly-related experience in toxicological pathology; or an equivalent combination of education, training and/or experience from which comparable knowledge, skill and abilities have been attained.
  • Board Certification from the American College of Veterinary Pathologists is required.
  • Must have a demonstrated, thorough knowledge of animal anatomy, medicine, physiology and pathology as well as working knowledge of histology, clinical pathology, surgery, pharmacology, bacteriology, virology, parasitology, mycology, biochemistry and other related disciplines. The candidate must also have a demonstrated understanding of the fundamentals of research methodology, principles and procedures.
  • The Pathologist must have superior professional-level written and verbal communication skills; strong interpersonal and organizational skills, and the ability to effectively work independently and as part of a team of researchers. Must have professional-level computer skills in Microsoft Office, as well as the ability to learn department-specific computer systems as needed.
  • Requires the ability to work in containment facilities (ABSL-3+, etc.) which may require vaccinations/immunizations, background checks and other fitness for duty test, and the ability to gain and maintain access to Kirtland Air Force Base (KAFB).

Preferred/Additional Qualifications

  • A PhD in biomedical science, as well as previous experience in industry or contract research organization (CRO) settings, is preferred.
  • Prior experience in infectious disease research and/or animal disease model development, toxicologic and/or infectious disease pathology are also desired.

Salary
Salary is commensurate with experience.

EEO, including disability/vets

Equal Opportunity Employer

The Lovelace Biomedical Research Institute Companies are an Equal Opportunity employer-M/F/Veteran/Disability. We are committed to the hiring, advancement and fair treatment of all individuals, and all qualified applicants will receive consideration for employment without regarding to race, color, religion, sex, national origin, sexual orientation, gender identity, age, disability, protected veteran status, or any other protected status as designated by federal, state or local law. All applicants and employees are further protected from discrimination based on inquiring about, disclosing or discussing the compensation of other applicants or employees.

For assistance with our application process, including reasonable accommodations for individuals with disabilities to participate in the application process, please send an email to recruiting@lovelacebiomedical.org or call 505-348-9400.

Boehringer Ingelheim, Biberach, Germany—Principal Scientist Toxicologic Pathology

Posted:
Company: Boehringer Ingelheim
Location: Biberach, Germany
Job Title: Principal Scientist Toxicologic Pathology

The Position

Are you looking to apply your scientific expertise and enhance your experience as Toxicologic Pathologist? Are you agile, self-motivated and responsible with a pro-active mindset?

Boehringer Ingelheim is a globally leading and family-owned pharmaceutical company with a substantial commitment to innovative Research and Development. The campus in Biberach an der Riss is Boehringer Ingelheim’s most significant R&D site for human pharmaceuticals. It is located in Southern Germany, not far from the Alps, the Lake of Constance, Stuttgart and Munich.

The position is available within the Pathology Group of our Nonclinical Drug Safety Department in Biberach and offers a broad range of challenging tasks, assisting the Group Manager, with focus on the following areas:

Tasks & Responsibilities

  • In your new role, you act as study pathologist on early exploratory and regulatory toxicity studies to include input on study design, contribution of gross and microscopic evaluation and integrated reporting.
  • You perform peer reviews of in-house studies and studies performed at CROs.
  • Furthermore, you provide technical guidance to pathology laboratory personnel in compliance with GLP, company safety and regulatory guidelines.
  • With your scientific expertise, you develop new technologies and strategies, which help to elucidate mechanisms of toxicity.
  • You contribute to interdisciplinary developmental projects and to phase-transition and regulatory submission documents.

Requirements

  • Doctor of Veterinary Medicine, a PhD is a plus
  • Board certified ECVP or ACVP or equivalent
  • Several years of work experience in Toxicologic Pathology in a GLP environment is preferred
  • Scientific and technical experience in special pathology techniques (e.g. immunohistochemistry, electron microscopy, AI) is a plus
  • Strong scientific interest and analytical capacity, target- and strategy-oriented work attitude
  • Open-minded personality and strong team player
  • Excellent communication skills and fluency in English, written and verbally

READY TO CONTACT US?
Please contact our HR Direct Team, Tel: +49 (0) 6132 77-3330.
Apply until: 31.01.2024
Please include the following documents when applying for this position: CV, Cover letter
Discover our Biberach site: xplorebiberach.com

Our Company
At Boehringer Ingelheim we develop breakthrough therapies that improve the lives of both humans and animals. Founded in 1885 and family-owned ever since, Boehringer Ingelheim takes a long-term perspective. Now, we are powered by 52,000 employees globally who nurture a diverse, collaborative and inclusive culture. We believe that if we have talented and ambitious people who are passionate about innovation, there is no limit to what we can achieve.

Why Boehringer Ingelheim?
With us, you can grow, collaborate, innovate and improve lives.

We offer challenging work in a respectful and friendly global working environment surrounded by a world of innovation driven mindsets and practices. In addition, learning and development for all employees is key, because your growth is our growth.

Boehringer Ingelheim is an equal opportunity global employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment, which benefits our employees, patients and communities.

Want to learn more? visit boehringer-ingelheim.com

Moderna, Cambridge, MA—Postdoctoral Fellowship in Toxicologic Pathology

Posted:
Company: Moderna
Location: Cambridge, MA
Job Title: Postdoctoral Fellowship in Toxicologic Pathology

Applications are invited for the Joint Academic Pharmaceutical Postdoctoral Fellowship Program in Toxicologic Pathology. This program is offered by Purdue University in partnership with Moderna. The fellow will be expected to actively participate in research and development efforts in the Department of Non-clinical Sciences in Cambridge, MA (onsite), the R&D headquarters of Moderna.

Under the guidance of ACVP board-certified pathologists at Moderna, the fellow will conduct pathologic evaluations to understand the potential toxicity of modified mRNAs and delivery systems in preclinical species. Additionally, the fellow will engage in scientific research, incorporating data from tissue investigative techniques such as IHC, IF, ISH, multiplex assays, spatial profiling, image analysis, and microphysiologic systems like organ-on-a-chip.

The Fellow will have the opportunity to help uncover the molecular pathogenesis behind toxicity-related changes to understand if these effects could translate to clinical situations. Fellow will explore molecular and cellular mechanisms of toxicity to identify drivers of liver, cardiovascular, and other toxicities, thereby guiding drug projects to create safer medicines using their experience, in-house data, and literature data. The successful candidate is expected to collaborate with team members across related disciplines and communicate pathology data clearly and concisely in both oral and written reports. Publishing manuscripts and presenting at scientific conferences and other scientific forums are strongly encouraged.

Eligibility

DVM (or equivalent degree). Successful applicants will have completed a 3-year residency training in Veterinary Pathology or met the eligibility requirements to take the board examination administered by the American College of Veterinary Pathologists (ACVP) or ACVP board certification.

Start Date

The position is available to start as soon as possible, and renewable for up to two years.

Starting Salary—$80,267 plus benefits

How to apply—For inquiries about this fellowship, please contact Shan Naidu or Nobuko Wakamatsu Utsuki.

Regeneron Pharmaceuticals, Tarrytown, New York—Toxicologic Pathology Externship (Summer 2024)

Posted:
Company: Regeneron Pharmaceuticals
Location: Tarrytown, New York
Job Title: Toxicologic Pathology Externship (Summer 2024)

Summary

Regeneron's Department of Drug Safety and Pharmacometrics is offering a 2-week externship in toxicologic pathology. This externship will take place at Regeneron's corporate site, which is focused on all phases of drug development and is staffed with seven board-certified Anatomic Pathologists with innovative microscopic imaging and analysis facilities.

In this role, a typical day might include:

  • Microscopic pathology experience with a variety of strains of rodents (mice and rats)
  • Experience with digital pathology and image analysis in the context of discovery and preclinical safety assessment
  • A preview of the activities of a toxicologic pathologist in a pharmaceutical company
  • Access to transgenic rodents, which provides a strong background in animal species that are not traditionally assessed in an academic residency training

This role might be for you if:

  • You are currently a resident in an anatomic pathology training program or are a Veterinary Pathology fellow who has previously completed a pathology residency.
  • You wish to further your training in and exposure to toxicologic and rodent pathology.
  • You are a highly motivated fourth-year veterinary student with experience in pathology and a demonstrable interest in toxicologic pathology.
  • You are self-motivated and have a clear and demonstrable interest and ongoing experience in anatomic pathology, particularly histopathology.

Applicants should be enrolled in a veterinary anatomic pathology residency with at least one year of experience evaluating diagnostic case material or be employed in a fellowship. Veterinary student candidates should be enrolled in an AVMA-accredited veterinary college in their 4th year. This is a paid externship (housing is not provided).

Applications should include curriculum vitae, contact information for three references, and a letter of interest describing professional background, interests and goals, and pathology experience and preparation.

Deadline to apply for 2024 externships: January 2, 2024. The position starts summer of 2024.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.

Link to Apply: https://regeneron.wd1.myworkdayjobs.com/Careers/job/TARRYTOWN/Toxicologic-Pathology-Externship--Summer-2024-_R25915

UCB–Toxicologic Pathologist

Posted:
Company: UCB, Inc.
Location: Cambridge, MA
Job Title: Toxicologic Pathologist

Make your mark for patients

UCB is looking for an exceptional Toxicologic Pathologist to join our Development Science team as part of our expanding Boston R&D HUB team in Cambridge, MA. We’re also open to the position being based out of either our Brussels, Belgium or Slough, UK R&D Hubs.

Job Summary/Overview:

  • Provide expertise and guidance across the global UCB portfolio
  • Identify pathology related safety risks within emerging projects and experimental strategies to mitigate those risks
  • Provide insight and strategic input for management on the effective use of new advances in investigative pathology
  • Provide scientific interpretation of pathology study results, conduct primary microscopic evaluation and pathology peer reviews
  • Contribute and support interactions with regulatory agencies and post-marketing activities
  • Define and deploy the toxicological pathology strategy applied to our projects

Major Accountabilities:

  • Serve as Project Pathologist and Subject Matter Expert on assigned compounds: Contribute to the design of in-vivo studies, provide histopathological microscopic examination (primary read and Peer Review), interpretation and reporting of toxicology studies to characterize safety or efficacy and enable decision-making or benefit-risk assessment in support of progressing these compounds to patients.
  • Collaborate with internal (Study Monitors, Safety representatives, Project Team Members, and stakeholders) & external partners (CROs and consultant pathologists). Contribute and support interactions with regulatory agencies and post-marketing activities
  • Apply digital pathology solutions and molecular pathology techniques, in conjunction with histology scientists to support quantitative pathology
  • Collaborate with the Histology team to develop new molecular pathology assay and markers to address specific project needs, apply new technologies that help progress compounds to patients and ensure delivery of high-quality project support. Maintain an awareness of new / emerging techniques and tools relevant to the field.
  • Provide expert pathology evaluation of safety data on potential in-licensing candidates to assess their suitability for further development by UCB.

Interested? For this role we’re looking for the following education, experience, and skills:

  • DVM and relevant Ph.D.
  • Diplomate of the American or European College of Veterinary Pathologists (DACVP or DECVP)
  • 10+ years of experience in toxicologic pathology, preferably in both CROs and the pharmaceutical industry, 5+ years of which have been spent in drug discovery and development.
  • Proven experience in digital pathology and image analysis, molecular pathology, and related methods
  • Work morale, dedication, proactivity, professionalism, scientific expertise, innovative ideas, and proven leadership abilities
  • Breaking silos and demonstrating influential leadership beyond the role (transversal collaboration and shared accountability)

Salary Range: $194,480 to $255,255

Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you! Apply Now!

About Us

UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.

Why Work for us

At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected and has equitable opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.

UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/colour/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.

US FDA CFSAN Office of Dietary Supplement Programs—Supervisory Interdisciplinary Scientist

Posted:
Company: US FDA CFSAN Office of Dietary Supplement Programs
Location: Remote
Job Title: Supervisory Interdisciplinary Scientist

Summary

  • Title 21 Vacancy Announcement
  • Department of Health and Human Services (HHS)
  • Food and Drug Administration (FDA)
  • Center for Food Safety and Applied Nutrition (CFSAN)
  • Office of Dietary Supplement Programs (ODSP)
  • Division of Research and Evaluation (DRE)
  • Safety Evaluation Branch (SEB)
  • Branch Chief, (Supervisory Interdisciplinary Scientist)

Application Period
August 18, 2023–September 29, 2023

Area of Consideration
United States Citizenship is required. You must be a US Citizen or US National. Foreign nationals or legal permanent residents are not eligible for consideration.

Series
0405 (Pharmacologist); or 0415 (Toxicologist)

Salary
Starting at $132,368

Full Performance Band Level
Band D

Position
Branch Chief, (Supervisory Interdisciplinary Scientist), Safety Evaluation Branch

Location(s)
Remote

Work Schedule
Full Time

Cures Band(s)
Band D

Travel Requirements:
Up to 25%

Bargaining Unit
8888, Non-Bargaining Unit

Relocation Expenses Reimbursement
You may qualify for reimbursement of relocation expenses in accordance with agency policy.

This position is being filled under a stream-lined hiring authority, Title 21, Section 3072 of the 21st Century Cures Act. The candidate selected for this position will serve under a career or career-conditional appointment and be paid under the provisions of this authority.

Apply Online!

Boehringer Ingelheim, Biberach, Germany—Senior Principal Scientist Toxicologic Pathology (m/w/d) (ID: 236658)

Posted:
Company: Boehringer Ingelheim
Location: Biberach, Germany
Job Title: Senior Principal Scientist Toxicologic Pathology (m/w/d) (ID: 236658)

OUR COMPANY

At Boehringer Ingelheim we develop breakthrough therapies and innovative healthcare solutions in areas of unmet medical need for both humans and animals. As a family owned company, we focus on long-term performance. We believe that, if we have talented and ambitious people who are passionate about innovation, there is no limit to what we can achieve; after all, we started with just 28 people. Now, we are powered by 50,000 employees globally who nurture a diverse, collaborative and inclusive culture.

THE POSITION

Take advantage of your scientific expertise and work experience and apply it to key challenges in the drug development process. Contribute actively to the success of new therapeutics to help improve the quality of human life.

Boehringer Ingelheim is a globally leading and family-owned pharmaceutical company with a substantial commitment to innovative Research and Development. The campus in Biberach an der Riss is Boehringer Ingelheim’s most significant R&D site for human pharmaceuticals. It is located in Southern Germany, not far from the Alps, the Lake of Constance, Stuttgart and Munich.

The position is available within the Pathology Group of our Nonclinical Drug Safety Department in Biberach and offers a broad range of challenging tasks, assisting the Group Manager, with focus on the following areas:

Discover our Biberach site: xplorebiberach.com

Tasks & Responsibilities

  • You contribute your profound and broad toxicologic pathology expertise to the preclinical development of drug candidates.
  • You guide troubleshooting with classical methods and innovative strategies in case of unexpected study results.
  • Additionally, you act as study pathologist and perform peer reviews of in-house studies and studies performed at CROs.
  • You assume delegated responsibility for histopathology peer review and study report review of carcinogenicity studies.
  • As expert, you ensure training and counseling of other colleagues within the group.
  • You contribute to interdisciplinary non-clinical developmental projects and to phase-transition and regulatory submission documents.
  • Furthermore, you establish and maintain a network with other company sites, academia and industry in order to achieve optimum investigative strategies and scientific results within the preclinical development process.

Requirements

  • Doctor of Veterinary Medicine; a PhD is a plus
  • Board certified ECVP or ACVP or equivalent
  • Long-standing work experience in Toxicologic Pathology in a GLP environment, including carcinogenicity studies, following board certification
  • Excellent knowledge of relevant regulatory standards in toxicology and related fields of drug development
  • Experience in non-clinical development projects highly desirable
  • Strong scientific interest and analytical capacity, target- and strategy-oriented work attitude
  • Willing to accept new challenges, flexible in mind, autonomous and reliable
  • Open-minded personality and strong team player
  • Excellent communication skills and fluency in English, written and verbally

Recruitment process

Step 1: Online application - application deadline is 10.07.2023
Step 2: Virtual meeting scheduled for mid-July
Step 3: On-site interviews end of July/beginning of August

WHY BOEHRINGER INGELHEIM?

This is where you can grow, collaborate, innovate and improve lives.

We offer challenging work in a respectful and friendly global working environment surrounded by a world of innovation driven mindsets and practices. In addition, learning and development for all employees is key, because your growth is our growth. We also offer a competitive salary, generous amount of vacation time, and numerous benefits towards your wellness & financial health and work-life balance. Plus, an onsite gym (Ingelheim), in-house doctor and best-in-class cafeterias and coffee bars to keep you energized and healthy. To learn more about what benefits could be waiting for you, please visit our Career area.

Want to learn more about us? Visit https://www.boehringer-ingelheim.com/

Boehringer Ingelheim is an equal opportunity global employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment, which benefits our employees, patients and communities. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or national origin.

READY TO CONTACT US?

Please contact our Recruiting Team, Tel: +49 (0) 6132 77-173173

Not exactly the position you are looking for but have someone else in mind? Share it via the link below with friends or colleagues who might be interested.

Apply Online!

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