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Current Postings
Posted:
Company: Charles River Laboratories
Location: Mattawan, Michigan
Job Title: Clinical Pathologist II
For more than 75 years, Charles River employees have worked together to assist in the discovery, development, and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. The Mattawan site is near Kalamazoo in Southwest Michigan and is one of the world’s largest contract research organization sites. Our pathology team in Mattawan is composed of over a dozen pathologists with extensive knowledge on a wide variety of compounds, animal models and study designs. The pathology team is a cohesive unit and enjoy the benefits of intradepartmental consultations and collaborations. We encourage and accommodate flexible and virtual workplace opportunities.
Job Responsibilities:
- Responsible for the interpretation of clinical pathology data and preparation of comprehensive clinical pathology reports
- Aid Study Directors in the interpretation of clinical pathology endpoints
- Serve as Study Clinical Pathologist or Principal Investigator on studies
- Interact with Anatomic Pathologists to ensure relevant and appropriate correlations for clinical and anatomical pathology endpoints
- Evaluate study specimens related to clinical pathology, such as blood smears, bone marrow smears, urinalysis sediment preparations and body fluid preparations. Evaluate other materials as necessary and appropriate
- Provide scientific expertise for experimental design and conduct of research studies
- Participate in method development, and identification and evaluation of new instrumentation, as required
- Assist in expanding the array of clinical pathology assays to meet contemporary needs and expectations
- Assist in on-site employee training in clinical pathology or related topics as needed for studies, specialty projects or continuing education
- Provide expertise and guidance to Clinical Pathology personnel with technical issues
- Review and approve new/revised Standard Operating Procedures (SOPs) pertaining to pathology. Confirm department SOPs are developed and maintained according to established guidelines.
Qualifications for the Clinical Pathologist II position include, but are not limited to:
- DVM/VMD (Doctor of Veterinary Medicine) degree or equivalent required
- Board certification by the American College of Veterinary Pathologists (ACVP) with specialty in Clinical Pathology (or equivalent) required
- An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
Compensation Info:
The pay range for this position is $170,000-$180,000. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.
Apply Online!
Posted:
Company: NIEHS/Division of Translational Toxicology (DTT)
Location: Durham, NC
Job Title: Staff Scientist
NIEHS is seeking a staff scientist for Mouse Embryo Phenotyping (MEP) group within CMPB, in DTT, at NIEHS. MEP work is project-driven and supports divisional interdisciplinary investigators to advance its mission of providing broad support and training in mouse embryo phenotyping techniques in support of the NIEHS vision and mission. The scientific goals for MEP are achieved through a distinct and highly cooperative and integrated team science operational model, providing project assistance through the utilization of shared NIEHS Core facilities. A principal role for this position is to assist NIEHS investigators in assigning molecular underpinnings to developmental phenotypes encountered in genetically modified mouse models.
The staff scientist will manage and be the lead contact for all project submissions to the MEP group. The staff scientist partners with a team consisting of a histologist and pathologist with expertise in developmental biology, tissue handling and pathology tailored to embryo phenotyping of genetically engineered mice under study.
Additionally, the MEP staff scientist collaborates across the Institute to stay abreast of novel approaches and best practices for the integration of information technology and other solutions that may serve to scientifically advance projects submitted to the MEP group.
Apply Online!
Posted:
Company: Genentech Inc.
Location: South San Francisco, CA
Job Title: Principal Scientist, Pathology
The successful Translational Safety Principal Pathologist candidate will provide scientific leadership and play an active role in the process of drug development from target assessment through marketed products. Working in a team environment, Translational Safety Project Pathologists participate in and may lead the strategic design, implementation, and data analysis of non-GLP investigative and GLP regulatory studies to ensure the comprehensive, highly integrated safety profiling of Genentech drug candidates.
Apply Online!
Posted:
Company: Immunome
Location: Bothell, WA
Job Title: Director, Pathology
Company Overview:
Immunome is a clinical-stage targeted oncology company committed to developing first- and best-in-class targeted therapies designed to improve outcomes for cancer patients. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge targeted cancer therapies, including antibody-drug conjugate therapies (ADCs.).
Position Overview:
The Director, Pathology will develop and implement comprehensive plans to support optimal nonclinical packages for candidate drugs in all stages of development from developing liability assessments and advising on early screening assays to submission of NDA/BLAs. In this role, they will lead the design, development, and implementation of discovery, interpretation of target expression, and exploratory pathology plans for multiple oncology programs, enabling the optimal clinical development of candidate drugs.
Job Responsibilities:
- Act as a pathology and pathogenesis subject matter expert in Translational Sciences, providing key strategy and analysis cross-functionally for discovery, target expression interpretation, and animal models.
- Provide pathology support for exploratory and development (e.g. GLP) pathology endpoints on internal and external in vivo studies across the pipeline.
- Provide expert authorship and/or review of regulatory submissions (e.g. INDs, IBs, CTDs, BLAs).
- Executes on the plans to provide high quality data to support internal decision making and regulatory submissions.
- Actively partners with other functions and departments to ensure that programs are progressed seamlessly through the development process.
- Participates in assessment of in-license assets to provide a recommendation to senior management.
Qualifications:
- Board-certified in veterinary pathology (ACVP/ECVP) required.
- PhD, PharmD, MD, or equivalent in a relevant scientific discipline (e.g. biology, toxicology).
- 4+ years' experience, preferably with large molecule experience.
- Global regulatory filing (NDA/BLA) experience preferred.
Knowledge and Skills:
- Experience with designing and reporting out exploratory pathology studies and comparative biomarker assays.
- Excellent skills in assessment of the appropriate toxicology experiments to support clinical development at all stages of product development. Demonstrated experience supporting regulatory compliant nonclinical development plans, with excellent working knowledge of the regulatory process. Engagement in cutting edge technologies which improve decision making and align with regulatory partners.
- Excellent problem-solving skills and ability and desire to oversee multiple projects simultaneously in a fast-paced environment.
- Ability to drive collaboration, achieve results, influence, and resolve conflicts across internal and external project teams.
E/E/O
Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
Apply Online!
Posted:
Company: Immunome
Location: Bothell, WA
Job Title: Senior Director, Pathology
Company Overview
Immunome is a clinical-stage targeted oncology company committed to developing first- and best-in-class targeted therapies designed to improve outcomes for cancer patients. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge targeted cancer therapies, including antibody-drug conjugate therapies (ADCs.).
Position Overview
The Senior Director, Pathology will develop and implement comprehensive plans to support optimal nonclinical packages for candidate drugs in all stages of development from developing liability assessments and advising on early screening assays to submission of NDA/BLAs. In this role, they will lead the design, development, and implementation of toxicology plans and pathology solutions for multiple oncology programs, enabling the optimal clinical development of candidate drugs
Job Responsibilities:
- Author relevant sections of clinical protocols and regulatory submissions (such as IBs, CTDs, INDs, BLAs).
- Proactively develops plans to provide stage specific data for all assets from late-stage research through regulatory submission for drug approval. Executes on the plans to provide high quality data to support internal decision making and regulatory submissions.
- Provide pathology support for exploratory and development (e.g. GLP) pathology endpoints on internal and external in vivo studies across the pipeline.
- Actively partners with other functions and departments to ensure that programs are progressed seamlessly through the development process.
- Act as a pathology and pathogenesis subject matter expert in Translational Sciences.
- Participates in assessment of in license assets to provide a recommendation to senior management.
Qualifications:
- Board-certified in veterinary pathology (ACVP/ECVP) required.
- Ph.D., PharmD, MD, or equivalent in a relevant scientific discipline (e.g. biology, toxicology).
- 10+ years' experience in pharmaceutical/biotechnology industry, preferably with large molecule experience.
- Experience in successful submission of at least three global filings for First in Human Trials (NDA/BLA).
Knowledge and Skills:
- Excellent skills in assessment of the appropriate toxicology experiments to support clinical development at all stages of product development. Demonstrated experience supporting regulatory compliant nonclinical development plans, with excellent working knowledge of the regulatory process.
- Engagement in cutting edge technologies which improve decision making and align with regulatory partners.
- Working knowledge of the most advanced exploratory and investigative toxicology methods to interrogate putative target and/or platform-related liabilities.
- Ability to drive collaboration, achieve results, influence, and resolve conflicts across internal and external project teams.
E/E/O
Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
Apply Online!
Posted:
Company: Virscio Inc.
Location: New Haven, CT
Job Title: Director of Pathology
The Director of Pathology coordinates preclinical pathology research plans and analysis to support preclinical safety and efficacy studies, including those involving disease models and their characterization.
Job Responsibilities:
- Leadership: Lead the pathology function of the research platform by providing pathology expertise for conducted studies and supervising the pathology and image analysis teams. Lead pathology execution and reporting of histopathology SOWs with annual targets established with the CEO and CBO.
- Statement of Work Development: Provide pathology expertise to development of the histopathology component of protocols and histopathology SOWs. Contribute to and approve pathology SOW plans and amendments.
- Data Management: Ensure pathology data acquisition, quality control, collation, and analysis are conducted in accordance with study protocols, SOWs, SOPs, and best practice. Supervise these activities within pathology and image analysis teams.
- Documentation: Supervise documentation procedures for all SOWs to ensure data and events, including unanticipated finding or test system responses, and their peer review are accurately verified and documented within pathology and image analysis teams.
- QC/QA: Apply processes to ensure study data (paper and electronic records) and study reports undergo appropriate quality control and Quality Assurance (QA) review, as appropriate, prior to reporting or external distribution. Contribute to SOP maintenance and preparation for compliance audits and respond to QA findings. Supervise these activities within pathology and image analysis teams.
- Study Reporting: Complete pathology final reports and oversee their generation by other pathologists and contributors.
- Sponsor Communication: Provide pathology expertise in support of communications related to sponsor program support.
- Third-Party Engagement: Engage subcontracted laboratories, vendors, and consultants in the evaluation and application of external or new research capabilities required to achieve and report study endpoints. Lead these activities within pathology and image analysis teams.
- Business Development: Present company research capabilities and outcomes in client teleconferences and relevant scientific conferences (poster or oral data presentation is a criterion for conference attendance). Lead and guide preparation of manuscript for publication and material to be presented at meetings and conferences by pathology and image analysis teams.
- Capability Expansion: Lead implementation of improved pathology capabilities in consultation with the CEO and CBO and provide training/consultation where appropriate.
Qualifications:
- Requires DVM & ACVP board certification, or equivalent.
- Minimum 15 years preclinical pathology experience, including 10 years NHP exp.
- Expertise in primate pathology and comparative anatomic pathology.
Location:
Remote USTravel Expectations:
5 to 10% to attend conferences as a presenter and travel to company sites.Apply Online!
Posted:
Company: Weill Cornell Medicine/MSKCC- CCMP LCP
Location: New York, NY
Job Title: Fellowship in Comparative and Genomic Pathology
The Laboratory of Comparative Pathology (LCP) of Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, Hospital for Special Surgery, and The Rockefeller University is accepting applications for a 15-month postdoctoral fellowship in comparative and genomic pathology for veterinary pathology trainees seeking to advance their knowledge in these disciplines.
The fellow takes advantage of a large and diverse laboratory animal caseload and state-of-the-art facilities housed within the LCP, providing capacity for necropsy, histology, immunohistochemistry, in situ hybridization, whole slide digital image analysis, hematology, clinical chemistry, microbiology, parasitology, and serology. Other core facilities housed within the institutions provide access to in vivo imaging, transmission and scanning electron microscopy, confocal microscopy, and laser capture microdissection equipment and expertise.
Responsibilities include performing gross pathologic and histopathologic examinations of a variety of laboratory animal species (mice, rats, hamsters, rabbits, guinea pigs, pigs, non-human primates, fish, amphibians), interpreting findings, preparing reports, and communicating with clinical veterinarians and research personnel. Scientific collaborations and publications are encouraged. Supervision by 3 board-certified pathologists (ACVP and/or ECVP) is provided. The fellow participates in didactic activities held jointly with the Tri-Institutional Training Program in Laboratory Animal Medicine & Science, including Histopathology and Gross Pathology Rounds, Clinical and Pathology Conference, Laboratory Animal Medicine Seminar Series, and Journal Club.
Applicants must possess a DVM/VMD from an AVMA-accredited or equivalent institution and have completed at least 2 years of residency anatomic pathology training. Preference will be given to candidates who have completed 3 years of anatomic veterinary pathology training. Salary is based on the NIH post-doctoral scale and commensurate with experience. Complete application materials will be reviewed on a rolling basis until the position is filled.
Applicants should submit a letter of intent describing interests, career goals, and past pathology and research experiences, curriculum vitae, veterinary and graduate school (if applicable) education transcripts, and three letters of recommendation. Referees should send their letters directly to Dr. Sebastián Carrasco. Application materials and questions should be addressed to:
Sebastián Carrasco DVM, MPVM, MSc, PhD, Dipl. ACVP
Laboratory of Comparative Pathology
Center of Comparative Medicine and Pathology
Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine
1275 York Avenue, Box 270, New York, NY 10065
Email: CarrascS@mskcc.org
Posted:
Company: College of VetMed, University of Illinois at Urbana-Champaign (UIUC)
Location: Urbana, IL
Job Title: Open Rank Specialized or Tenure Track in Molecular Diagnostics
The Veterinary Diagnostic Laboratory at the College of Veterinary Medicine, University of Illinois at Urbana-Champaign (UIUC) invites applications for a faculty position at the rank of tenure track or clinical track open rank. The Veterinary Diagnostic Laboratory serves the State of Illinois, the College of Veterinary Medicine, and many national and international medicine and research groups. This position is a full-time, twelve-month appointment and is available beginning on or around January 16, 2025.
Requirements:
Candidates must possess a DVM and PhD with experience in host/tissue based molecular pathology. Advanced pathology training, experience in diagnostic veterinary medicine and excellent communication/interpersonal skills are preferred.
The successful candidate will function in the areas of diagnostic services, teaching and scholarly activity. Integration of the latest in genomic technologies and computational biology to diagnose diseases in a range of animal species using techniques such as tissue micro arrays, in situ hybridization, genomics, digital pathology, image analysis and informatics. Collaborations should be developed with diagnostic veterinary pathologists, molecular virologists and microbiologists. Additionally, collaboration with clinicians including comparative oncologists, wildlife and exotic animal veterinarians, and companion animal and large animal internists is expected. There are numerous opportunities for collaboration with groups on the Urbana campus including Cancer Center, bioengineering, Woese Institute for Genomic Biology, Beckman institute and Neuroscience program.
Salary:
The budgeted salary range for this position is $110,000 to $140,000. The pay offered to the selected candidate will be determined based on factors including (but not limited to) the experience and qualifications of the selected candidate including equivalent years in rank, training, and field or discipline; internal equity; and external market pay for comparable positions. A summary explanation of these benefits can be found at https://www.hr.uillinois.edu/benefits.
Personal Opportunities:
Urbana-Champaign offers the residential advantages of a medium-sized university city, excellent cultural opportunities, and a high quality of life. In 2023, Forbes ranked the University of Illinois Urbana-Champaign as #9 among all US public colleges, on the basis of return on investment, student success, student debt, and alumni leadership and influence. Only one other campus featuring a veterinary college ranked above Illinois.
Application Procedures:
Please create a candidate profile through jobs.illinois.edu. In order to receive full consideration, applications must be received December 15, 2024. Applicants may be interviewed before the closing date; however, no hiring decision will be made until after that date. If you are interested or would like additional information on the position, please contact:
Dr. Arnon Gal,
Assistant Professor
Department of Veterinary Clinical Medicine
Veterinary Diagnostic Laboratory
agal2@illinois.edu
The University of Illinois System is an equal opportunity employer, including but not limited to disability and/or veteran status, and complies with all applicable state and federal employment mandates. Please visit Required Employment Notices and Posters to view our non-discrimination statement and find additional information about required background checks, sexual harassment/misconduct disclosures, COVID-19 vaccination requirement, and employment eligibility review through E-Verify. Applicants with disabilities are encouraged to apply and may request a reasonable accommodation under the Americans with Disabilities Act (2008) to complete the application and/or interview process. Requests may be submitted through the reasonable accommodations portal, or by contacting the Accessibility & Accommodations Division of the Office for Access and Equity at 217- 333-0885, or by emailing accessibility@illinois.edu
Posted:
Company: Alnylam
Location: Cambridge, MA
Job Title: Director, Pathology
OVERVIEW:
Alnylam has a full-time opening for a board-certified veterinary pathologist to help our research and development activities associated with a broad portfolio encompassing CNS, ocular, liver, adipose, oncology, and muscle targets for siRNA therapeutic candidates. The successful applicant will support Alnylam programs from early discovery through IND filings and beyond. The pathologist will consult with research scientists and toxicologists on target development and study design for investigational and registrational studies for potential new drug candidates. Pathology support will be provided for drug target platforms and programs through histopathology evaluation/interpretation, photomicrograph documentation of key findings, scientific data presentations, peer review of outsourced studies, and pathology issue resolution/adversity assessment. The candidate will join a vibrant experienced pathology team with broad internal capabilities. Candidates with 6 or more years of experience are considered for the Director position. Individuals with appropriate skill sets and interest/experience with Alnylam portfolio related fields of emphasis are encouraged to apply. Alnylam pathologists are supported by a highly experienced pathology laboratory staff with a broad range of standard and specialized pathology (IHC, ISH, digital imaging, spatial image analysis) tools are readily employed to support a broad range of scientific investigations. Alnylam’s proprietary RNAi platform is ideally positioned to address genetically defined diseases. Come help us translate this promise into medicine.
SUMMARY OF KEY RESPONSIBILITIES:
- Pathology assessment of internal and external preclinical research studies for platform and program support; includes interpretation of histochemical and molecular pathology tools (IHC and ISH)
- Peer review for outsourced nonGLP and GLP studies
- Clearly report findings and significance to program teams and broader audiences through descriptions, data tables, photomicrographs, and scientific presentations
- Contribute pathology reports for regulatory filings
- Consult with other internal and external stakeholders on preclinical study design and interpretation
- Actively participate in program and platform meetings
- Interact with necropsy and histology team members to assure consistency in tissue collection and staining
- Share expertise across Research and Early Development
- Participate in group, department and company meetings and activities
QUALIFICATIONS:
The successful candidate is expected to have the following qualifications:
- Veterinary degree and ACVP/ECVP board certification; PhD preferred but not required in lieu of pathology experience
- Experience in Pharma and/or Contract Research Organizations
- Demonstrated scientific curiosity
- Interest in molecular pathology, digital pathology, and spacial pathology tools.
- Strong interest in one or more areas of Alnylam research emphasis; demonstrated experience preferred
- Strong communication skills and ability to deliver polished presentations
- Ability/interest to travel for company needs including peer review
- Onsite or hybrid roles in proximity to Cambridge are strongly preferred.
- Fluency in oral and written English
- Ability to multitask and work in a fast-paced environment
- Excellent interpersonal skills and collegiality
- If employed in the US, being fully vaccinated against COVID-19 as defined by the Centers of Disease Control and Prevention (CDC) is required.
Apply Online!
Posted:
Company: W.L. Gore & Associates Inc.
Location: Flagstaff, AZ
Job Title: Veterinary Pathologist
We are looking for a Veterinary Pathologist to join our team! Medical device pathology at Gore offers a dynamic and rewarding work context in which the pathologist’s expertise is a critical input throughout device development, from early prototype iteration to mature product safety testing. In this role, you will be a member of the Biosciences’ Pathology team that supports the development of state-of-the art implantable medical devices, including but not limited to vascular grafts, endovascular and interventional devices, cardiac devices, surgical meshes, and sutures. You will utilize pathology training and experience to assess the performance and safety of medical devices in various animal models and implant locations in a regulated environment. Come join us in our mission to improve lives, together!
Apply Online!
Posted:
Company: Yale University School of Medicine
Location: New Haven, CT
Job Title: Veterinary Pathologist
The Department of Comparative Medicine at the Yale University School of Medicine is searching for an academic veterinary pathologist with a strong research focus to pursue independent and collaborative research, participate in training of laboratory animal medicine residents, and provide, on a rotational basis, diagnostic pathology services. The Pathology Unit provides necropsy, microbiology, histology and health surveillance support for the Yale Animal Resources Center, which maintains more than 120,000 animals ranging from zebrafish to nonhuman primates, with the majority comprised of genetically engineered mice.
The Department of Comparative Medicine has a full-time faculty of 38 veterinarians, physicians, and basic scientists with robust federally funded research programs in metabolism, neurobiology, stem cells, vascular biology, cardiopulmonary biology and COVID. Comparative animal model development and with a strong translational and collaborative focus has been identified as a strategic area of research growth within the Department.
This position is being requested to provide pathology diagnostic support to Veterinary Clinical Services (a unit of the Yale Animal Resources Center) and to expand programmatic research that aligns with Comparative Medicine’s strategic plan of advancing comparative animal model development and translation. One of the current diagnostic veterinary pathologists will shift a large portion of effort to research pathology and will as needed support the diagnostic service or teaching and training activities within Comparative Medicine’s Laboratory Animal Medicine Training Program. Pathology replacement effort is needed to support the veterinary pathology diagnostic service and meet pathology teaching/training responsibilities. An independent or well-established collaborative research track record is anticipated to fulfill the research expectations of the position.
Apply Online!
Posted:
Company: The Ohio State University
Location: Columbus, OH
Job Title: Senior Research Open Faculty Search - Comparative/Laboratory Animal Pathology
The Department of Veterinary Biosciences in the College of Veterinary Medicine, in conjunction with the James Comprehensive Cancer Center at The Ohio State University is seeking applicants for a clinical-track faculty position at the Assistant or Associate Professor level in Comparative/Laboratory Animal Pathology.
As a member of the Comparative Pathology & Digital Imaging Shared Resource (CPDISR), the comparative pathologist will provide pathology expertise and support for investigator-initiated research with an emphasis on preclinical toxicity/efficacy studies and the phenotypic characterization of genetically modified mice to researchers utilizing animal models. The CPDISR is committed to leveraging digital imaging and new analytical approaches to enhance understanding of disease mechanisms and accelerate drug discovery. Thus, expertise in and/or interest to develop expertise in new analytical approaches is highly desirable, and collaboration on research grants is encouraged. In addition to contributing to CPDISR activities, the successful candidate will be actively involved in training of veterinary students and veterinary pathology residents in the OSU-CVM combined pathology residency/Ph.D. program.
The position is predominantly research pathology service with an opportunity for collaborative research (70%), teaching (20%) and administrative service (10%).
Education and Experience Requirements
Required:
- DVM or equivalent from an AVMA-accredited or equivalent institution
- Board-certification by or board-eligibility for the American or European College of Veterinary Pathology
Desired:
- PhD
- Demonstrated background in pathobiology of laboratory animals
- Demonstrated expertise and support for investigator-initiated research
- Experience in digital image analysis
- Experience in, or knowledge to assist in, the development of new analytical approaches
- Evidence of collaboration and/or Co-PI on research grants
- Scholarly track-record consistent with rank
- Experience in the classroom and laboratory teaching of veterinary students
- Experience in the training of anatomic and/or clinical pathology residents
- Evidence of mentoring (e.g. students, trainees, staff, peer)
- Evidence of supporting a culture of collegiality and academic citizenship
To view full job description and submit the requested materials with your online application, please visit: https://osujoblinks.com/witn
Review of applications will begin immediately and continue until the position is filled.
Required documents include:
- Cover Letter
- Curriculum Vita (CV)
- Statement of Scholarship
- Statement of Teaching and Mentoring
Additional information regarding this search or the position, can be obtained by contacting Stefan Niewiesk, DVM, PhD, Diplomate, ECLAM at niewiesk.1@osu.edu.
All qualified applicants will receive consideration for employment without regard to age, ancestry, color, disability, ethnicity, gender, gender identity or expression, genetic information, HIV/AIDS status, military status, national origin, pregnancy, race, religion, sex, sexual orientation, or veteran status.
Posted:
Company: Merck & Co., Inc
Location: West Point, PA
Job Title: Senior Principal Scientist
Our Company is a leading global biopharmaceutical company with over 125-year history of Inventing for Life with an inspiring mission to make discoveries that positively impact global healthcare. Our success is driven by putting patients first, operating with the highest integrity, and committing fully to our vision to make a difference in the lives of people globally. With our diverse pipeline of vaccines, biologics, small molecules, and newer modalities, we are at the forefront of research to advance the prevention and treatment of diseases such as cancer, cardiometabolic diseases, Alzheimer’s disease, eye diseases, and infectious diseases including HIV, and Ebola.
Our Company's Research Laboratories’ nonclinical safety assessment group at the West Point, Pennsylvania site is seeking an experienced anatomic pathologist to join a highly collaborative team of scientists (14 anatomic pathologists, 3 clinical pathologists, and approximately 40 exceptional technical staff), working at a GLP-compliant facility with state-of-the-art anatomic, molecular and clinical pathology laboratories. Our team works on a diverse and exciting pipeline, participating in a wide variety of GLP-toxicology study types, many of which are run in-house, in addition to early discovery and investigative studies.
Pathologists at our company are integral members and leaders of collaborative cross functional scientific teams, addressing challenges from early discovery to late development. Our Company’s pathologists provide scientific leadership in the design and conduct of postmortem evaluation of studies and integrate the interpretation of postmortem data into the safety profile of drug candidates. Our Company's pathologists have diverse opportunities to learn and grow as professional scientists and drug developers through daily study related activities and collaborative works with diverse program development teams.Key responsibilities for this scientific role include:
- Employ both routine H&E evaluations as well as other specialized techniques to characterize the safety profile of new drugs from toxicology and investigative studies
- Serve as Program Pathologist, providing scientific input and oversight across studies from very early discovery to late stage development, following molecules throughout their lifetime
- Communicate with study team/drug development teams on study findings and participate on cross-functional teams to elucidate mechanisms of toxicity, and may be required to provide advanced scientific and/or technical guidance to technical and/or Ph.D/D.V.M. level staff. Utilizing additional tools and applications that are all available on-site, including:
- An industry-leading suite of on-site in vitro and in vivo assay capabilities
- Access to robust historical controls slide archive and data base
- Transmission electron microscopy
- Immunohistochemistry and in situ hybridization
- Quantitative digital image analysis and targeted machine learning applications
- In vivo imaging tools (e.g., magnetic resonance imaging)
- Develop novel biomarkers and predictive models to de-risk drug candidates for safety-related liabilities
- Our Company's pathologists also serve as nonclinical safety assessment leads on drug development teams, overseeing the design and execution of studies, and generation of regulatory strategy and communications with global regulatory agencies to support the development of drug candidates
- Our Company's pathologists work in a hybrid work environment and routinely interact with each other, share slides and opinions/experiences, and help each other learn and grow
Required experience and skills:
- Love to collaborate with diverse cross-functional teams and communicate openly and often with colleagues
- Doctor of Veterinary Medicine (DVM)
- Residency in anatomic/toxicologic pathology
- ACVP or ECVP-board certification in anatomic pathology
- Over 5 years of experience as a pathologist in biotech, pharma or at a CRO
Preferred experience and skills:
- Demonstrated proficiency in histomorphologic evaluation and interpretation of rodent carcinogenicity studies
- Strong knowledge of the drug discovery, development and regulatory processes, including experience on drug development project teams
- PhD in Toxicology, Pathology, or related discipline
- Experience in ophthalmic pathology
Our Company has a commitment to the continued professional development of all colleagues through training opportunities, publications, internal and external presentations, access to internal scientific seminars as well as support for external scientific meetings. With our location along the Northeastern US corridor, there are many opportunities to participate in cross-industry workshops, conferences, direct regulatory interactions and other training or networking opportunities. Imagine what you could achieve at our Company!
We are a research-driven biopharmaceutical company. Our mission is built on the premise that if we “follow the science” great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.
Who we are …
We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.
What we look for …
In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.
Posted:
Company: Takeda
Location: Boston, MA
Job Title: Scientific Director, Pathology
About This Role:
At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.
Join Takeda as a Director, Pathology Drug Safety Research and Evaluation (DSRE), Head of Investigative Pathology (iPath) in Cambridge, MA, where you will manage a team of scientists and technicians, oversee all pathology activities, and act as the pathology subject matter expert on cross-functional research and development teams. The Head of Investigative Pathology is a strategic and hands-on leadership role responsible for driving pathology support for programs, providing expert guidance and oversight in investigative and toxicologic pathology within Drug Safety Research and Evaluation (DSRE). This role combines lab management and project support with a focus on delivering high-quality, timely data to primarily support early-stage drug discovery and toxicology studies.
As part of the DSRE, Pathology team, you will report to the Senior Director DSRE - Pathology and you will partner with senior management and R&D teams to align pathology goals with overall program objectives.
How you will contribute:
- Manage the iPath Laboratory, ensuring compliance with all regulatory and safety standards.
- Lead, mentor, and develop a team of scientists, and technical staff to achieve project milestones.
- Manage lab operations, budgeting, resource allocation, and workflows to optimize efficiency and productivity.
- Proven leadership experience in managing pathology labs and teams in a discovery and nonclinical setting.
- Oversee and drive the development of investigative pathology capabilities within the team, including innovative methods to advance project outcomes.
- Provide scientific direction and investigative pathology expertise to project specific IHC and ISH deliverables in collaboration with the project pathologist.
- Serve as an integral member on discovery and development project teams to collaborate with project and R&D leadership across Takeda to ensure transition of programs into development.
- Responsible for recognizing critical issues as a highly skilled specialist, effectively communicate their implications to a broad audience and develop strategies investigate/derisk these data to impact the project team strategy and decision making.
- Collaborate with DSRE project representatives, cross-functional project teams, Global Head of Pathology and Drug Safety Therapeutic Area Leaders in the development and execution of nonclinical safety and investigative strategies for discovery and development stage programs.
- Provide training and knowledge sharing for pathology-related aspects across the R&D teams.
- Participate in local and national toxicology/pathology meetings and represent Takeda in professional society committees, working groups and cross industry consortia.
Minimum Requirements/Qualifications:
- DVM (or equivalent) and Ph.D. degree in a scientific discipline are both required.
- Board certified by the American College of Veterinary Pathologists (ACVP), European College of Veterinary Pathology (ECVP) or Japanese College of Veterinary Pathology (JCVP) is required.
- Pharmaceutical drug development experience preferably including as a project team Pathologist (10+ years).
- Proven leadership experience in managing pathology labs and teams in a discovery and nonclinical setting.
- In-depth understanding of molecular biology with strong expertise in toxicologic pathology and its application to drug discovery and development.
- Excellent communication (written and oral), leadership, and team-building skills, with the ability to work in a collaborative environment.
- Proficiency with Microsoft Office suite, HALO/HALO Link, Pristima (or other pathology data capture systems), Patholytix.
More About Us:
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy. This position requires the candidate to come onsite to Cambridge location minimum 5x/month.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Boston, MA
US Base Salary Range:
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
US based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. US based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
| Locations | Worker Type |
| Boston, MA | Employee |
| Worker Sub-Type | Time Type |
| Regular | Full time |
Posted:
Company: Biogen
Location: Cambridge, MA
Job Title: Senior Director, Head of Pathology
About This Role:
Biogen is seeking a visionary Senior Director, Head of Pathology to spearhead our dynamic Pathology Group within the Nonclinical Safety department. In this pivotal role, you will provide scientific leadership, people management, and strategic direction, ensuring the delivery of top-quality pathology services for our diverse portfolio of drug discovery and development programs. Your expertise will be instrumental in guiding cross-functional teams and propelling Biogen's mission of developing innovative therapies in neurology, immunology, and rare diseases. As a key member of the Nonclinical Safety Leadership Team, your contributions will be critical to our ongoing commitment to patient care and scientific excellence.
What You’ll Do:
- Lead and manage the Pathology Group, setting strategic vision and fostering talent development.
- Ensure high-quality pathology input to both discovery and development stage programs.
- Represent pathology on the Nonclinical Safety Leadership Team, overseeing departmental operations.
- Collaborate with cross-functional teams to achieve shared goals and advance drug candidates.
- Act as a Nonclinical Safety delegate on various internal/external committees and groups.
- Manage resource allocation, budgeting, and operational planning within the pathology function.
- Drive innovative approaches to pathology as part of new technology initiatives where applicable.
Who You Are:
You are an experienced toxicologic pathologist with a passion for leadership and people management. With broad knowledge of nonclinical safety assessment and a history of success in pharmaceutical drug development, you shine in communication and organizational skills. As a collaborative team player across research, drug discovery and/or development, you're eager to take on expanded responsibilities and make a significant impact in a groundbreaking biotech environment.
Required Skills:
- Minimum 15 years of relevant experience
- Must have Pharma, Biotech and/or CRO experience
- DVM or equivalent
- Board Certification required
- Proven people management capabilities
- Profound expertise in toxicologic pathology
- Knowledge of GLP and other applicable regulatory requirements
- Demonstrated ability to work within cross-functional teams
Required Skills:
- PhD
Why Biogen?
Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients’ lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.
Apply NowPosted:
Company: Altasciences
Location: Everett, WA
Job Title: Senior Research Pathologist
Your New Company!
At Altasciences we all move in unison to assist and work in the discovery, development, and manufacturing of new drug therapies to get them faster to people who need them. No matter your role, we all play an important part and you will have a significant impact on the health and well-being of people across the globe. By living our values of Employee Development, Customer Focus, Quality and Excellence, Respect and Integrity, we look to foster a passionate and collaborative work environment and we are looking for talented and enthusiastic people, like you, to join our growing team! Whether you’re a recent college graduate or seeking your next career opportunity, it’s time to discover your future at Altasciences. We are better together and together We Are Altasciences.
About the Role
Altasciences is seeking an experienced Senior Research Pathologist (Anatomic) to support preclinical toxicologic studies run primarily at the Everett, Washington site and on occasion, from other preclinical sites. This is considered an onsite role as the candidates would support technical groups and collaborate closely with other anatomic and clinical pathology colleagues at the Everett facility.
What You’ll Do Here
- Perform macroscopic and microscopic tissue evaluations and interpretation of assigned studies
- Assist with necropsy supervision and gross pathology interpretation. Guiding of personal staff for sample collection and technical development
- Write comprehensive report narratives detailing all test article effects
- Enter pathology findings in data capturing system
- As needed, work with study directors to ensure data is accurately integrated into study reports
- Provide training, technical guidance and leadership to laboratory staff
- Maintain an up-to-date knowledge in toxicologic pathology
- May serve as principal investigator for contract pathology work, participate in pathology working group (PWG) as an observer and serve as a consultant in pathology-related issues
- May provide scientific expertise for experimental design and other aspects of research studies, as needed.
- Act as pathology representative for important sponsors
- Provide mentorship (study scientific reviews) on assigned studies to less experienced pathologists.
- Ability to build strong bonds with technicians to foster open, honest and candid communications
- Ability to multi-task and stay organized in a fast paced, changing environment.
- Provide training, technical guidance and leadership to laboratory staff, pathology trainees, and less experienced pathologists.
What You’ll Need to Succeed
- D.V.M. (or Equivalent as listed by AVMA ECFVG®) required
- MSc/MVSc and/or Ph. D. is preferred
- Diplomate of ACVP, JCVP, ECVP or RCP strongly preferred
- At least 3-5 years of toxicologic pathology experience in a GLP environment is preferred by exceptional candidates with less experience will still be considered.
- Experience with evaluation of special stains and IHC and/or specialty pathology expertise (ie, CNS, dermal, ocular, and/or carcinogenicity studies) is highly desirable
- *Exceptional candidates with less experience will be considered
What We Offer
The pay range estimated for this position is $185,000 to $200,000 per year. Please note that hourly rates/salaries vary within the range based on factors including, but not limited to, prior relevant experience, skills, education, certification, location as well as internal equity and market data.
Altasciences offers a wide variety of benefits to help our employees live healthy and fulfilling lives both at and outside of work.
Altasciences' Benefits Package Includes
- Health/Dental/Vision Insurance Plans
- 401(k)/RRSP with Employer Match
- Paid Vacation and Holidays
- Paid Sick and Bereavement Leave
- Employee Assistance & Telehealth Programs
Altasciences' Incentive Programs Include
- Training & Development Programs
- Employee Referral Bonus Program
- #LI-BK1
Altasciences' Incentive Programs Include
- Job Family: Doctor
- Pay Type: Salary
