Access ToxPathNet
ToxPathPic
Follow us
Advertise on the STP website to reach your target audience effectively and economically!
Current Postings
Posted:
Company: Regeneron Pharmaceuticals Inc.
Location: Tarrytown, NY
Job Title: Associate Director, Pathology
Regeneron is looking for an Associate Director of Pathology.
A Typical Day In This Role May Look Include
The position reports to the Senior Director of Pathology and has primary responsibility to support drug molecule efficacy and safety studies in a variety of therapeutic focus areas (TFAs). The successful candidate will also provide histopathology evaluation support and immunopathology oversight for GLP toxicology and PK studies of REGN molecules. The Associate Director will be expected to manage Pathology support to selected TFAs, act as lead Pathologist on project teams and mentor junior Pathologists.
This Role Might Be For You If Can/have:
- Participate in strategy development in Drug Safety and Pharmacometrics (DSP) through advocacy for REGN programs and projects
- Responsible for pathologic evaluation of drugs and actively collaborate with R&D, regulatory and clinical scientists to facilitate the actualization of Regeneron’s Strategic Plan
- Apply knowledge to help design, develop, and implement research programs to support all facets of drug development
- Perform pathology peer review of REGN toxicology studies at CROs (and therefore must be GLP-trained)
- Participate on project teams dedicated to developing predictive and prognostic biomarkers.
Collaborate to develop strong in-house digital pathology program
To be considered for this opportunity, you must have the following:
- Doctor of Veterinary Medicine (DVM) or equivalent (with Ph.D. preferred) in Comparative Pathology (or other biomedical field)
- Board Certification in Anatomic Veterinary Pathology (DACVP or DECVP)
Experience:
- 0-5 years of toxicologic pathology experience for Senior Pathologist/Principal Pathologist/Associate Director; position title will commensurate with experience
- Proven productivity in investigative/experimental pathology research evidenced by publications is desirable
- Experience with regulatory studies, including assessment of biologics studies
- Familiarity with molecular pathology and image analysis techniques
- Strong interpersonal and communication skills, with the ability to collaborate effectively with diverse stakeholders
Please Note: This is an onsite role based out of our Tarrytown, NY office. If you are not local and qualify, a relocation package can be offered.
Apply Online!
Posted:
Company: Charles River Laboratories
Location: Mattawan, Michigan
Job Title: Clinical Pathologist II
For more than 75 years, Charles River employees have worked together to assist in the discovery, development, and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. The Mattawan site is near Kalamazoo in Southwest Michigan and is one of the world’s largest contract research organization sites. Our pathology team in Mattawan is composed of over a dozen pathologists with extensive knowledge on a wide variety of compounds, animal models and study designs. The pathology team is a cohesive unit and enjoy the benefits of intradepartmental consultations and collaborations. We encourage and accommodate flexible and virtual workplace opportunities.
Job Responsibilities:
- Responsible for the interpretation of clinical pathology data and preparation of comprehensive clinical pathology reports
- Aid Study Directors in the interpretation of clinical pathology endpoints
- Serve as Study Clinical Pathologist or Principal Investigator on studies
- Interact with Anatomic Pathologists to ensure relevant and appropriate correlations for clinical and anatomical pathology endpoints
- Evaluate study specimens related to clinical pathology, such as blood smears, bone marrow smears, urinalysis sediment preparations and body fluid preparations. Evaluate other materials as necessary and appropriate
- Provide scientific expertise for experimental design and conduct of research studies
- Participate in method development, and identification and evaluation of new instrumentation, as required
- Assist in expanding the array of clinical pathology assays to meet contemporary needs and expectations
- Assist in on-site employee training in clinical pathology or related topics as needed for studies, specialty projects or continuing education
- Provide expertise and guidance to Clinical Pathology personnel with technical issues
- Review and approve new/revised Standard Operating Procedures (SOPs) pertaining to pathology. Confirm department SOPs are developed and maintained according to established guidelines.
Qualifications for the Clinical Pathologist II position include, but are not limited to:
- DVM/VMD (Doctor of Veterinary Medicine) degree or equivalent required
- Board certification by the American College of Veterinary Pathologists (ACVP) with specialty in Clinical Pathology (or equivalent) required
- An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
Compensation Info:
The pay range for this position is $170,000-$180,000. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.
Apply Online!
Posted:
Company: Genentech Inc.
Location: South San Francisco, CA
Job Title: Principal Scientist, Pathology
The successful Translational Safety Principal Pathologist candidate will provide scientific leadership and play an active role in the process of drug development from target assessment through marketed products. Working in a team environment, Translational Safety Project Pathologists participate in and may lead the strategic design, implementation, and data analysis of non-GLP investigative and GLP regulatory studies to ensure the comprehensive, highly integrated safety profiling of Genentech drug candidates.
Apply Online!
Posted:
Company: Immunome
Location: Bothell, WA
Job Title: Director, Pathology
Company Overview:
Immunome is a clinical-stage targeted oncology company committed to developing first- and best-in-class targeted therapies designed to improve outcomes for cancer patients. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge targeted cancer therapies, including antibody-drug conjugate therapies (ADCs.).
Position Overview:
The Director, Pathology will develop and implement comprehensive plans to support optimal nonclinical packages for candidate drugs in all stages of development from developing liability assessments and advising on early screening assays to submission of NDA/BLAs. In this role, they will lead the design, development, and implementation of discovery, interpretation of target expression, and exploratory pathology plans for multiple oncology programs, enabling the optimal clinical development of candidate drugs.
Job Responsibilities:
- Act as a pathology and pathogenesis subject matter expert in Translational Sciences, providing key strategy and analysis cross-functionally for discovery, target expression interpretation, and animal models.
- Provide pathology support for exploratory and development (e.g. GLP) pathology endpoints on internal and external in vivo studies across the pipeline.
- Provide expert authorship and/or review of regulatory submissions (e.g. INDs, IBs, CTDs, BLAs).
- Executes on the plans to provide high quality data to support internal decision making and regulatory submissions.
- Actively partners with other functions and departments to ensure that programs are progressed seamlessly through the development process.
- Participates in assessment of in-license assets to provide a recommendation to senior management.
Qualifications:
- Board-certified in veterinary pathology (ACVP/ECVP) required.
- PhD, PharmD, MD, or equivalent in a relevant scientific discipline (e.g. biology, toxicology).
- 4+ years' experience, preferably with large molecule experience.
- Global regulatory filing (NDA/BLA) experience preferred.
Knowledge and Skills:
- Experience with designing and reporting out exploratory pathology studies and comparative biomarker assays.
- Excellent skills in assessment of the appropriate toxicology experiments to support clinical development at all stages of product development. Demonstrated experience supporting regulatory compliant nonclinical development plans, with excellent working knowledge of the regulatory process. Engagement in cutting edge technologies which improve decision making and align with regulatory partners.
- Excellent problem-solving skills and ability and desire to oversee multiple projects simultaneously in a fast-paced environment.
- Ability to drive collaboration, achieve results, influence, and resolve conflicts across internal and external project teams.
E/E/O
Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
Apply Online!
Posted:
Company: Immunome
Location: Bothell, WA
Job Title: Senior Director, Pathology
Company Overview
Immunome is a clinical-stage targeted oncology company committed to developing first- and best-in-class targeted therapies designed to improve outcomes for cancer patients. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge targeted cancer therapies, including antibody-drug conjugate therapies (ADCs.).
Position Overview
The Senior Director, Pathology will develop and implement comprehensive plans to support optimal nonclinical packages for candidate drugs in all stages of development from developing liability assessments and advising on early screening assays to submission of NDA/BLAs. In this role, they will lead the design, development, and implementation of toxicology plans and pathology solutions for multiple oncology programs, enabling the optimal clinical development of candidate drugs
Job Responsibilities:
- Author relevant sections of clinical protocols and regulatory submissions (such as IBs, CTDs, INDs, BLAs).
- Proactively develops plans to provide stage specific data for all assets from late-stage research through regulatory submission for drug approval. Executes on the plans to provide high quality data to support internal decision making and regulatory submissions.
- Provide pathology support for exploratory and development (e.g. GLP) pathology endpoints on internal and external in vivo studies across the pipeline.
- Actively partners with other functions and departments to ensure that programs are progressed seamlessly through the development process.
- Act as a pathology and pathogenesis subject matter expert in Translational Sciences.
- Participates in assessment of in license assets to provide a recommendation to senior management.
Qualifications:
- Board-certified in veterinary pathology (ACVP/ECVP) required.
- Ph.D., PharmD, MD, or equivalent in a relevant scientific discipline (e.g. biology, toxicology).
- 10+ years' experience in pharmaceutical/biotechnology industry, preferably with large molecule experience.
- Experience in successful submission of at least three global filings for First in Human Trials (NDA/BLA).
Knowledge and Skills:
- Excellent skills in assessment of the appropriate toxicology experiments to support clinical development at all stages of product development. Demonstrated experience supporting regulatory compliant nonclinical development plans, with excellent working knowledge of the regulatory process.
- Engagement in cutting edge technologies which improve decision making and align with regulatory partners.
- Working knowledge of the most advanced exploratory and investigative toxicology methods to interrogate putative target and/or platform-related liabilities.
- Ability to drive collaboration, achieve results, influence, and resolve conflicts across internal and external project teams.
E/E/O
Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
Apply Online!
Posted:
Company: Virscio Inc.
Location: New Haven, CT
Job Title: Director of Pathology
The Director of Pathology coordinates preclinical pathology research plans and analysis to support preclinical safety and efficacy studies, including those involving disease models and their characterization.
Job Responsibilities:
- Leadership: Lead the pathology function of the research platform by providing pathology expertise for conducted studies and supervising the pathology and image analysis teams. Lead pathology execution and reporting of histopathology SOWs with annual targets established with the CEO and CBO.
- Statement of Work Development: Provide pathology expertise to development of the histopathology component of protocols and histopathology SOWs. Contribute to and approve pathology SOW plans and amendments.
- Data Management: Ensure pathology data acquisition, quality control, collation, and analysis are conducted in accordance with study protocols, SOWs, SOPs, and best practice. Supervise these activities within pathology and image analysis teams.
- Documentation: Supervise documentation procedures for all SOWs to ensure data and events, including unanticipated finding or test system responses, and their peer review are accurately verified and documented within pathology and image analysis teams.
- QC/QA: Apply processes to ensure study data (paper and electronic records) and study reports undergo appropriate quality control and Quality Assurance (QA) review, as appropriate, prior to reporting or external distribution. Contribute to SOP maintenance and preparation for compliance audits and respond to QA findings. Supervise these activities within pathology and image analysis teams.
- Study Reporting: Complete pathology final reports and oversee their generation by other pathologists and contributors.
- Sponsor Communication: Provide pathology expertise in support of communications related to sponsor program support.
- Third-Party Engagement: Engage subcontracted laboratories, vendors, and consultants in the evaluation and application of external or new research capabilities required to achieve and report study endpoints. Lead these activities within pathology and image analysis teams.
- Business Development: Present company research capabilities and outcomes in client teleconferences and relevant scientific conferences (poster or oral data presentation is a criterion for conference attendance). Lead and guide preparation of manuscript for publication and material to be presented at meetings and conferences by pathology and image analysis teams.
- Capability Expansion: Lead implementation of improved pathology capabilities in consultation with the CEO and CBO and provide training/consultation where appropriate.
Qualifications:
- Requires DVM & ACVP board certification, or equivalent.
- Minimum 15 years preclinical pathology experience, including 10 years NHP exp.
- Expertise in primate pathology and comparative anatomic pathology.
Location:
Remote USTravel Expectations:
5 to 10% to attend conferences as a presenter and travel to company sites.Apply Online!
Posted:
Company: Weill Cornell Medicine/MSKCC- CCMP LCP
Location: New York, NY
Job Title: Fellowship in Comparative and Genomic Pathology
The Laboratory of Comparative Pathology (LCP) of Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, Hospital for Special Surgery, and The Rockefeller University is accepting applications for a 15-month postdoctoral fellowship in comparative and genomic pathology for veterinary pathology trainees seeking to advance their knowledge in these disciplines.
The fellow takes advantage of a large and diverse laboratory animal caseload and state-of-the-art facilities housed within the LCP, providing capacity for necropsy, histology, immunohistochemistry, in situ hybridization, whole slide digital image analysis, hematology, clinical chemistry, microbiology, parasitology, and serology. Other core facilities housed within the institutions provide access to in vivo imaging, transmission and scanning electron microscopy, confocal microscopy, and laser capture microdissection equipment and expertise.
Responsibilities include performing gross pathologic and histopathologic examinations of a variety of laboratory animal species (mice, rats, hamsters, rabbits, guinea pigs, pigs, non-human primates, fish, amphibians), interpreting findings, preparing reports, and communicating with clinical veterinarians and research personnel. Scientific collaborations and publications are encouraged. Supervision by 3 board-certified pathologists (ACVP and/or ECVP) is provided. The fellow participates in didactic activities held jointly with the Tri-Institutional Training Program in Laboratory Animal Medicine & Science, including Histopathology and Gross Pathology Rounds, Clinical and Pathology Conference, Laboratory Animal Medicine Seminar Series, and Journal Club.
Applicants must possess a DVM/VMD from an AVMA-accredited or equivalent institution and have completed at least 2 years of residency anatomic pathology training. Preference will be given to candidates who have completed 3 years of anatomic veterinary pathology training. Salary is based on the NIH post-doctoral scale and commensurate with experience. Complete application materials will be reviewed on a rolling basis until the position is filled.
Applicants should submit a letter of intent describing interests, career goals, and past pathology and research experiences, curriculum vitae, veterinary and graduate school (if applicable) education transcripts, and three letters of recommendation. Referees should send their letters directly to Dr. Sebastián Carrasco. Application materials and questions should be addressed to:
Sebastián Carrasco DVM, MPVM, MSc, PhD, Dipl. ACVP
Laboratory of Comparative Pathology
Center of Comparative Medicine and Pathology
Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine
1275 York Avenue, Box 270, New York, NY 10065
Email: CarrascS@mskcc.org
Posted:
Company: College of VetMed, University of Illinois at Urbana-Champaign (UIUC)
Location: Urbana, IL
Job Title: Open Rank Specialized or Tenure Track in Molecular Diagnostics
The Veterinary Diagnostic Laboratory at the College of Veterinary Medicine, University of Illinois at Urbana-Champaign (UIUC) invites applications for a faculty position at the rank of tenure track or clinical track open rank. The Veterinary Diagnostic Laboratory serves the State of Illinois, the College of Veterinary Medicine, and many national and international medicine and research groups. This position is a full-time, twelve-month appointment and is available beginning on or around January 16, 2025.
Requirements:
Candidates must possess a DVM and PhD with experience in host/tissue based molecular pathology. Advanced pathology training, experience in diagnostic veterinary medicine and excellent communication/interpersonal skills are preferred.
The successful candidate will function in the areas of diagnostic services, teaching and scholarly activity. Integration of the latest in genomic technologies and computational biology to diagnose diseases in a range of animal species using techniques such as tissue micro arrays, in situ hybridization, genomics, digital pathology, image analysis and informatics. Collaborations should be developed with diagnostic veterinary pathologists, molecular virologists and microbiologists. Additionally, collaboration with clinicians including comparative oncologists, wildlife and exotic animal veterinarians, and companion animal and large animal internists is expected. There are numerous opportunities for collaboration with groups on the Urbana campus including Cancer Center, bioengineering, Woese Institute for Genomic Biology, Beckman institute and Neuroscience program.
Salary:
The budgeted salary range for this position is $110,000 to $140,000. The pay offered to the selected candidate will be determined based on factors including (but not limited to) the experience and qualifications of the selected candidate including equivalent years in rank, training, and field or discipline; internal equity; and external market pay for comparable positions. A summary explanation of these benefits can be found at https://www.hr.uillinois.edu/benefits.
Personal Opportunities:
Urbana-Champaign offers the residential advantages of a medium-sized university city, excellent cultural opportunities, and a high quality of life. In 2023, Forbes ranked the University of Illinois Urbana-Champaign as #9 among all US public colleges, on the basis of return on investment, student success, student debt, and alumni leadership and influence. Only one other campus featuring a veterinary college ranked above Illinois.
Application Procedures:
Please create a candidate profile through jobs.illinois.edu. In order to receive full consideration, applications must be received December 15, 2024. Applicants may be interviewed before the closing date; however, no hiring decision will be made until after that date. If you are interested or would like additional information on the position, please contact:
Dr. Arnon Gal,
Assistant Professor
Department of Veterinary Clinical Medicine
Veterinary Diagnostic Laboratory
agal2@illinois.edu
The University of Illinois System is an equal opportunity employer, including but not limited to disability and/or veteran status, and complies with all applicable state and federal employment mandates. Please visit Required Employment Notices and Posters to view our non-discrimination statement and find additional information about required background checks, sexual harassment/misconduct disclosures, COVID-19 vaccination requirement, and employment eligibility review through E-Verify. Applicants with disabilities are encouraged to apply and may request a reasonable accommodation under the Americans with Disabilities Act (2008) to complete the application and/or interview process. Requests may be submitted through the reasonable accommodations portal, or by contacting the Accessibility & Accommodations Division of the Office for Access and Equity at 217- 333-0885, or by emailing accessibility@illinois.edu
