In Memoriam

Glenn Howard Cantor, DVM, PhD, DACVP, 70, (https://www.linkedin.com/in/glenn-cantor-9383a48/) of Bend, Oregon, married to Inge Eriks for 43 years, died on February 16, 2024 in a snowmobiling accident in Alaska near Denali.

In a little over 3 weeks since Glenn’s passing was announced, a significantly richer view of our beloved Glenn emerged than even his immediate family professed to know through his favored social media. From one posting of Glenn’s story and 8 repostings, over 70,000 reads and hundreds of comments contributed to both a consistent view of Glenn our colleague and friend as well as a truly diverse collection of events that touched so many lives (https://www.linkedin.com/feed/update/urn:li:activity:7165319165749239809/). Glenn himself was an extremely detailed scientist and would have reveled in these data illustrating his particularly fine legacy.

Glenn’s career passed through the University of Michigan, University of Washington State University, Pharmacia, and Bristol-Myers Squibb. He retired in 2018, was subsequently highly sought for his consulting expertise.

Other authors have paid tribute to Glenn, the explorer, devoted family man, risk taker, photographer, teacher, biker, and storyteller. At his funeral, Inge recited an eloquently composed poem of Glenn as a fun-filled, family man devoted to nature. His daughters and brother relayed similar elements linked by a thread of intellectual curiosity and life-long learning. Glenn was striving to learn his wife’s native language of Dutch, having much earlier in his career mastered Spanish, Quechua, vegetable cropping and pig breeding as part of a Peace Corps operation in the jungles of Ecuador.

Glenn was a humble and good-humored man whose influence was derived from a combination of his depth of science and consummate story telling. Armed with these attributes, Glenn assumed key leadership roles in the Society of Toxicologic Pathology, Society of Toxicology and American College of Veterinary Pathologists, and recently the International Waldenstrom's Macroglobulinemia Foundation. He selflessly contributed many hours to these professional organizations at the highest level.

To attempt to be comprehensive in the context of this communication with someone such as Glenn is of course impossible, so I’ll limit this to one last vignette of which Inge, Glenn’s wife was unaware.

In the race to develop oral and intranasal small molecule CGRP inhibitors, BMS was in a horse race with Merck, Abbvie, Boehringer-Ingelheim and other pharmaceutical companies, when the intranasal program hit a snag. The lead molecule was pronounced dead, having produced significant nasal turbinate necrosis, without safety margins. After some time, Glenn working with others resurrected the molecule with a theory that the intranasal volume an morphology was initially incorrectly scaled to the human nose, and redesigned studies to assess the toxicologic potential, demonstrating, in fact, that the large initial volumes and their residence time had been incorrectly calculated and there was in fact sufficient safe margin to proceed. This connection, unbeknownst to many who considered Glenn more focused in other therapeutic areas, when in fact his skills were quite diverse, ultimately led to this compound’s registration as Zavspret® for intranasal treatment of migraine, arguably the fastest acting of all medicines in this field. The lead chemist on this project shared Glenn’s presentation with me, and I was reminded of the care he took with his photomicrography, the composition of micrographs and the stories he told.

Bruce Car

Kevin P. Keenan, DVM, PhD, Diplomate, ACVP, 77 of Doylestown, PA passed away Wednesday, October 18, 2023, after a brief illness. He was the beloved husband of Charlotte (Miller) Keenan.

Born October 19, 1945, in Boston Massachusetts, he was a son of the late Paul and Alice (Gannon) Keenan. Kevin spent the early years of his life in Massachusetts, most notably in Ipswich. He attended Essex Agricultural High School, raised poultry and vegetables in the backyard of the family home, and is still remembered by some of his former egg route customers.

Kevin then enrolled in the University of New Hampshire to study poultry science. Following two years of undergraduate education, he was accepted to the University of California School of Veterinary Medicine at Davis. An exceptionally hard worker with an unquenchable thirst for knowledge, Kevin completed both his undergraduate and Veterinary degrees in six years. Sandy McNeel, a veterinary school classmate remembers - Kev was one of my best friends during our four years of Veterinary School at Davis. In our second year of Vet School, we had great fun taking our puppies into the Haring Hall biochemistry lab in the evenings for combined study and puppy-training sessions. Then on Wednesday evenings (after study session, of course!), we adjourned to the Rathskeller for cheap beers on Ladies' Night and dancing to the juke box tunes, especially anything by Creedence Clearwater! Kev would also occasionally pile a bunch of us into his VW bug and cruise the university experimental gardens searching for giant vegetables to "liberate". He also was a gracious host at several memorable parties at the legendary house on Pole Line Road. We would spend wonderful hours before these events listening to vinyl records and creating the ultimate party tape. His sense of humor was epic, his loyalty to friends endless and his intellect boundless. He will be greatly missed by his legion of friends, colleagues, and everyone who knew him. Rest in peace, Kevin, my friend. And from J Craig Smith - the part of our lives we shared was epic, and unforgettable. You made me a better person by always making me think and challenging any extreme opinions I had. I’m so happy you had such a full life and accomplished more than you ever thought you would, always doubting how great you are. I’ll always remember you as my roommate, classmate, fellow hiker, traveler, buddy and the guy that could always make me laugh.

Following graduation from veterinary school, Kevin then entered the US Army Veterinary Corps as a Captain and spent time at the Walter Reed Army Institute of Research in Washington DC, working on canine viral diseases. Upon completing his tour of duty, Kevin entered private practice in California, doing both small and large animal work. Finding the hours grueling, the animals very ill and their owners often uncooperative, he was recruited back to the Veterinary Corps pathology department at Walter Reed to research tropical diseases. Henry Wall, a fellow veterinary pathologist, recalls - I was fortunate to have been selected for a summer externship in Veterinary Pathology at the WRAIR in 1974 after my 3d year of Veterinary school. I first met Kevin during that summer when I visited the WRAIR Kelser Laboratory at the Forest Glen campus where Kevin worked in Virology with Dr. Leonard Binn. I would occasionally see him in the WRAIR (Bldg 40) when he visited the Comparative Pathology Department, however, my interaction with him was limited as he was ending his initial active-duty tour during the summer of 1974. I really came to know him when he returned to active duty joining us as residents in veterinary pathology. Kevin and I would regularly share rides to almost monthly Davis Foundation Veterinary pathology training sessions at Ciba Geigy in Summit, NJ. Ralph Bunte accompanied us on many of these trips. Our trip conversations often dealt with veterinary pathology, but we usually included humorous conversations about a number of topics. Kevin's storytelling, humor, and quick wit was unmatched. When we discussed veterinary pathology topics Kevin could be counted on to provide succinct fact-rich explanation of disease processes, agents, and related tissue changes. He greatly aided our progress toward becoming veterinary pathologists. His stories of his character-building life experiences were always quite inspiring. My life was touched in positive ways by my experiences with Kevin. I truly believe it was part of his being to be a light in lives of all of us who knew him. Another pathology colleague, Carol Thompson noted that “Renaissance Man” comes to mind when I think of Kevin. His knowledge spanned numerous areas. He was well read, interested in many things, and could discuss various topics. Kevin was funny and had a great sense of humor. I do remember he was a great fan of the movie Star Wars. For a while after seeing the movie, anything in Kevin’s hand became a lightsaber that he would wave around with accompanying sound effects. Kevin treated me with kindness and respect. I cherish his friendship. He is missed.

At Walter Reed, Kevin met Captain Charlotte Miller, a fellow Veterinarian and recent graduate of the University of Pennsylvania. Charlotte was also assigned to the pathology department, and was drawn to Kevin’s profound intelligence, dedication to the work they shared, his usually affable personality and keen Irish wit. Kevin knew a good thing when he saw it; they fell in love and married in August of 1979. Now a Major, Kevin attended the University of Baltimore and obtained a PhD in Pathology under the tutelage of Dr. Elizabeth McDowell, Department of Pathology, School of Medicine with Department Chair Dr. Benjamin Trump. Elizabeth recalled their paths first crossed in the late 70s. At that time, my lab was studying various aspects of normal and abnormal changes in the bronchial lining, that part of the lung involved in most human lung cancers. Kevin became interested in an aspect of this work, and he embarked on a study of the bronchial surface following injury with his characteristic vigor, focus and determination. Now, looking back, it is surprising that our good working relationship and lifelong friendship ever happened, since I was a recent immigrant from England with paternal roots as a Presbyterian in Northern Ireland and he was Irish catholic! But we had common ground in being veterinarians and the same reaction to practice – liking the animals more than their owners. Our early career paths both launched us toward basic medical research. Kevin’s PhD work represented seminal research in injury and repair and my lab was very lucky to have had him work there. We got along well except for those times I thought I was “helping” edit some of his written work and we got into heated arguments about English versus American English. Following the completion of military service, Kevin taught at the University of Baltimore School of Medicine and continued the research into the origins of lung cancer. Kevin received board certification in Anatomic Pathology in 1983.

After the birth of their son Michael in 1986, the family moved to Doylestown Pennsylvania, where they made a life-long home and were blessed with wonderful friends and neighbors. Kevin worked diligently in the pharmaceutical industry at Merck Research Laboratories, directing his research to novel drugs intended for unmet needs in human diseases. He traveled extensively for his work, putting in many long, hard hours. Kevin always dove full bore into his projects and became particularly engaged in the research on ad libidum feeding in rodent carcinogenicity studies. The outcome of his work led many pharmaceutical laboratories to adopt a feeding regimen providing better survival in long term rodent studies. George Lankas, a toxicology colleague, recalls my fondest memories of Kevin were when I had a pathology or study-specific question and would find Kevin in his office, decorated with beautiful flowers from his garden. He always made time and would welcome me into his “homey” office for coffee or tea. Once we dispensed with work-related issues the conversation would veer to pigeons, deer hunting, or his latest trip to Maine. He was never at a loss for words, and I can easily summon the sound of his Boston accent. He was and always will be a valued colleague and friend who will be deeply missed. Carol McCoy worked closely with Kevin while at the Merck pathology laboratory. I always enjoyed his chipper greetings and how respectful he was to the technical staff. I was fortunate to become good friends with him while we worked on his ad libidum rodent feeding studies. He was a natural teacher, and I greatly enjoyed discussing our mutual interests in poultry, nature, bird watching and veterinary medicine. He entrusted me to care for his pigeons which he dove into with gusto just like he did with his research. I do not think he knew how much his kindness and friendship did for me. I miss him and often think of our conversations as I am caring for my animals. I will always hold closely the advice he often gave me: “Don’t let the turkeys get you down” or “this too will pass”. Kevin found peace and relaxation at his home, taking great pleasure in landscaping his property, and creating a backyard koi pond. Kevin, known for his tendency to minimize the scope of projects, told Charlotte he was going to get a few homing pigeons. Much to Charlotte’s exasperation, the “few” turned into over 100 racing pigeons and fancy birds. These birds were a lot of work and expense, and he loved them all because they allowed him to be involved with animals and nature and the outdoors. His quest for knowledge was limitless, and he was a voracious reader on a number of topics, especially history, nature, biology and the animal world. He enjoyed hunting trips to Maine with his brother Denis and hosting frequent visits from his brother Gavin and his family. For many years he greatly anticipated annual trips to Massachusetts in the late summer after the tourists had left. In retirement, Kevin maintained an intense interest in world affairs, much to his and his family’s chagrin. He enjoyed strolling the streets of downtown Doylestown, perusing the bookstores, and stopping at his favorite coffee shops. He was exceedingly proud of his son Michael when he earned a graduate degree in Physical Therapy and began his work in private practice. His world was made even brighter by Mikes marriage to Lindsey McGuire and fulfilled in a new and wonderful way by the births of his darling granddaughters, Kennedy and Kinley. Kennedy, at 6 yrs old, understood the loss and told us how much she will miss Pop-Pop reading books to her.

Kevin will be remembered for his intelligence, dedication to doing the right thing always, his generosity toward others, and especially his enduring love for his family. He loved and supported his nieces and nephews and was pleased with their accomplishments in life. Their admiration for him remains eternal. Kevin was passionate in his beliefs, did not suffer fools lightly, but always made allowances for their beliefs as well. He was good man and will be missed by us all.

Along with his wife, Charlotte, Kevin is survived by a son, Michael P. Keenan (Lindsey); 2 grandchildren, Kennedy and Kinley; his two brothers, Gavin Keenan (Josephine) and Denis Keenan (Melanie); niece, Sarah (Camila); and nephew, Patrick (Alyssa); brother-in-law Charles Miller; niece Jamie Keck; great-niece Taylor Keck (Bryan) and nephew Joseph Miller. Those who wish to make a memorial contribution in Kevin’s name can contribute to the STP Education Fund (Student Programs), the Audubon Society, Peace Valley Nature Center in Doylestown, or a charity of your choice

 

 

Michael R. Logan, 50, of Highland Park, IL passed away unexpectedly on June 30, 2023. He is survived by his wife Melissa, his son Andrew, 18, and his daughter Cammy, 16.

or of Veterinary Medicine degree in 1998. After graduating, Mike moved to Southern CA and completed his Veterinary Internship at West Los Angeles Animal Hospital where he met his wife, Melissa. During their 7 years in California, Mike became an avid surfer. As a hobby, Mike enjoyed designing and shaping surfboards.

Mike completed a residency in Veterinary Clinical Pathology as well as his Ph.D. at Purdue University in 2012. In 2005, they welcomed their son Andrew into their family followed by Cammy in 2007.

In 2014, Mike began his career with AbbVie as a Principal Pathologist. At AbbVie, Mike’s reach was felt far beyond his job description, as his personable nature and passion for science made him a true leader and trusted colleague. In 2022, Mike was promoted to Research Fellow. Mike was an active member of the Society of Toxicologic Pathology, where he chaired the Clinical Pathology Special Interest Group and co-chaired a CE course on Immune Biomarkers.

Mike was incredibly dedicated to his family. He cherished every moment he had with them and often said that his favorite place was by their side. It cannot be put into words what a wonderful father and loving husband he was and just how much he will be missed by them.

A fundraising campaign has been initiated and accounts have been established to ensure that Andrew and Cambria will get the education and support they deserve. Funds will be used for college, college-related expenses, special needs expenses, and savings for their future. Your generosity can have a significant impact on the lives of Andrew and Cambria.

If you would like to donate, please make checks payable to “Charles Schwab FBO Melissa Logan” and mail to the address below:

Ehlert Financial Group
103 Schelter Rd. Suite 10
Lincolnshire, IL 60069

For any questions or to donate via wire transfer or ACH please contact the Ehlert Financial Group at 847-522-8080 ext. 219.

Thank you in advance for your contribution in the memory of our very dear colleague and friend Mike Logan.

Magali R. Guffroy D.V.M., Diplomate ACVP; AbbVie, Distinguished Research Fellow

Richard A. Peterson II D.V.M., Ph.D., Diplomate ACVP; AbbVie, Research Fellow

Caitlyn M. Carter D.V.M., Diplomate ACVP; AbbVie, Senior Principal Veterinary Clinical Pathologist

On March 30, 2022, our honorary ESTP member, Professor Mohr, died at his home in Hannover, Germany, where he has lived with his family since 1976. He was buried in the family grave on April 13, 2022. Professor Mohr was born in 1931 in Frankfurt/Main and grew up in Frankfurt/Main and Munich.

After graduating from high school, he studied medicine in Munich, received his doctorate there (1958) and habilitated (1967) at the German Cancer Center in Heidelberg. His path to scientific success started here with the experimental proof of transplacental carcinogenesis.

In 1968 Prof. Mohr was appointed a full university professor and director of the Institute for Experimental Pathology at the Hannover Medical School. He held this position until 2000 when he retired. At that time his deep interest was in research of agents supposed to be carcinogenic to humans, in rodents for exploration and in vitro models with respiratory tissue. In 1981, Prof. Mohr was awarded with the German Research Prize for his work on the effects of PAHs on cell and organ cultures in vitro. He also paid particular attention to medical student training in histopathology. In addition to his duties at the Medical School Hannover, in 1982, he was a founding father of the Fraunhofer Institute of Aerosol Research in Hannover, which is located next to the university campus. After his retirement from the Hannover Medical school, Professor Mohr was a co-founder of the CULTEX labs (2007), which offered alternative techniques for exposure of cells to airborne pollutants, so that he could further pursue his scientific interests.

In 1978, Professor Mohr initiated and organized the annual ILSI Histopathology Seminars, which for nearly two decades provided training in laboratory animal pathology in Europe, the US and Japan, as a combination of oral presentations and glass slide seminars given by experts from all over the world. He also edited and co-edited a number of books essential in the field of toxicologic pathology with worldwide acceptance, such as the IARC WHO Monographs on "Pathology of Tumours in Laboratory Animals"—"Vol I Tumours of the Rat", "Vol 2 Tumours of the Mouse" and "Vol 3 Tumours of the Hamster", ten volumes of the "International Classification of Rodent Tumours, Part I—the Rat", and the textbook of the "International Classification of Rodent Tumours, the Mouse", as well as "Pathobiology of the Ageing Rat" and "Pathobiology of the Ageing Mouse". He was the editor of several monographs in the field of Inhalation Toxicology. His work contributed greatly to the training and continuing professional education of our membership. As director of the Fraunhofer Institute of Toxicology and Aerosol Research, Professor Mohr initiated in 1987, jointly with represent-tatives of chemical and pharmaceutical industry, the RITA project, a database of peer reviewed spontaneous tumors occurring in laboratory animals. The RITA project was one of the main drivers in establishment of internationally harmonized diagnostic criteria for neoplasms in rodents (INHAND), and which has been used intensely to the benefit of our membership.

Professor Mohr was the co-editor of the journal "Experimental Pathology", and later editor in-chief of the journal "Experimental and Toxicologic Pathology", which was the official journal of the GTP for many years. He was author or co-author of more than 600 scientific publications and supervisor of more than 90 doctoral theses and 21 habilitations. Professor Mohr received honorary doctorates from the University of Buenos Aires (Argentina), Barcelona (Spain), Kirov (Russia) and Chiang Mai (Thailand). In 2000, in recognition of his outstanding contributions to our society, Professor Mohr became honorary member of the GTP, which was transformed to the European Society of Toxicologic Pathology in 2002. With Professor Mohr we have lost a scientist with outstanding contributions to the education in laboratory rodent pathology. Furthermore, and even more important than his scientific achievements, Ulrich Mohr was a warm hearted, approachable personality. His direct and positive attitude to help and support was always a personal guidance for young scientists. We will miss this outstanding scientist, teacher, mentor, and fellow human being!

Thomas Nolte, Heinrich Ernst, Paul-Georg Germann, Susanne Rittinghausen

Dr. Gordon Hard, of Tairua, New Zealand, a preeminent international toxicology thought leader and international consultant in toxicologic pathology of the kidney, passed on November 22, 2021. He was a key player in shaping and developing the global field of toxicologic pathology and the role of toxicologic pathology in risk assessment of environmental chemicals and pharmaceuticals.

Gordon was born in Auckland, New Zealand in 1931. Dr. Hard received a BSc from the University of Auckland in 1955 and a Bachelor of Veterinary Science in 1959 from the University of Sydney (Australia). He then practiced veterinary medicine as Chief Veterinarian in the rural districts of Taihape and Raetihi in New Zealand. A moment of epiphany occurred when, after working all day and night, he crashed his car on a mountainous road and, in recovery, decided to go into pathology.

After receiving his PhD from The University of Sydney in 1968 and later a DSc from the University of Melbourne (Australia) in 1978, Dr. Hard worked with Professor Peter Magee in renal cancer research at the Fels Institute of Research at Temple University School of Medicine in Philadelphia where he was appointed as Professor. Thus began his specialization in renal carcinogenesis and chemical injury, beginning with several seminal papers about the nitroso compounds. He then became Head of Carcinogenesis Research at the University of New South Wales (Australia) and later Director and Chief Executive Officer (CEO) of the British Industrial Biological Research Association (BIBRA), Carshalton, Surrey, UK. Subsequently he served as Director of the American Health Foundation in Valhalla, New York, USA. He continued his research in renal toxicologic pathology, including consulting, while in those administrative roles. After stepping down from research leadership roles, which some would call retirement, he became a widely sought after renal pathology consultant to the pharmaceutical, chemical, consumer product and government organizations in North America, Europe and Japan. He published hundreds of scientific articles and many chapters, and also presented at a wide variety of meetings and venues, including teaching kidney pathology to future generations of toxicologic pathologists. Numerous awards attest to Dr. Hard’s valuable scientific contributions, including an Honorary Membership in the American College of Veterinary Pathologists in 2005 and the Lifetime Achievement Award from the Society of Toxicologic Pathology in 2017. He served as Editor-in-Chief of Toxicologic Pathology, Founding Editor‑in‑Chief for Toxicology in Vitro, and Editor‑in‑Chief for Food & Chemical Toxicology. He was also a Fellow of the Academy of Toxicological Sciences and the Royal College of Pathologists (London), and was awarded the DVSc from the University of Sydney for his research contributions.

Dr. Hard was multitalented, in his early years playing college soccer (University of Sydney) and semiprofessional soccer (Melbourne InterVarsity Football) in Australia. He had a love of music throughout his career, playing the keyboard for house guests. He snow skied every year well into his seventh decade. In a multifamily ski outing in Nevada, Gordon had everyone listen to his favorite “Tubthumping” by Chumbawamba, his favorite song. He was a student of nature with the ability to identify myriad plant and animal species. He particularly liked hosting visitors to his home in Tairua, with its spectacular views of the ocean, beaches, and mountains. He and his wife, Ruth, served as guides for many to the north island of New Zealand, educating the visitors about the history, nature, and beauty of his homeland for which he had great pride and many stories.

Dr. Hard is survived by his wife Ruth, daughter Cassandra Hard (Wentworth Falls, Australia) and sons Dr. James (Jake) J. Hard (Caerphilly, Wales), Nicolas (Nic) J.C. Hard (Benidoleig, Spain), 6 grandchildren and 3 great-grandchildren. He had dual citizenship in Australia/New Zealand, with resident status in the United States.

We have lost a pillar of the renal toxicology/pathology community and a gentleman and scholar in society.

Samuel M. Cohen, Wanda M. Haschek-Hock and Carl Alden

On June 6, 2019, the field of toxicologic neuropathology lost one of the most genuine and influential pathologists of this time, Dr. Georg Krinke. Dr. Krinke was born on May 12, 1943 in Czechoslovakia during difficult political times. Most of his early studies and veterinary school were conducted in Czechoslovakia. In 1963, he moved to Poland to complete a fellowship in veterinary medicine and in 1966, he received his DVM and completed postgraduate studies in neurochemistry back in Czechoslovakia. Dr. Krinke spent an additional year in West Germany conducting more postgraduate research in neuropathology (1970–1971), followed by eight years of research in histochemistry and in experimental pathology of laboratory animals at Ciba Geigy AG in Basel, Switzerland. From 1978 to 1986, he worked at The Institute of Neurotoxicology at Albert Einstein Medical College in the Bronx, New York. During that time, he also trained for two months at the Armed Forces Institute of Pathology (AFIP) in Washington, District of Columbia. In addition, Dr. Krinke worked for several agrochemical companies in Switzerland, including Novartis, Syngenta, and Anapath. In 1989, Dr. Krinke received a certification in pathology from the Swiss Veterinary Society. He became a member of the Society of Toxicologic Pathology in 1995 and was a full member for 24 years.

Dr. Krinke had a remarkable curriculum vitae that spanned 75 journal articles in various neuropathology topics, 31 book chapters, and 18 abstracts, and he was frequently invited to give oral presentations around the world. He was the first to pioneer publication of recommendations for sampling the nervous system and eye in laboratory animals. He also presented and published articles on the endocrine system and on spontaneous and xenobiotic-induced neoplasms in laboratory animals. Dr. Krinke worked, studied, and published several manuscripts on the mechanisms of neurotoxicity of environmental and pharmaceutical compounds, including organophosphorus pesticides, hexachlorophene, acrylamide, 2,5-hexanedione, pyridoxine (vitamin B6), clioquinol, and guanethidine.

Dr. Krinke was a unique scholar who loved to teach and was a neuropathology mentor to many colleagues, in accordance with his belief that sharing knowledge is the best contribution to the neuropathology field. He was one of the most open-minded neuropathologists, as exemplified by the occasion when he and Dr. Klaus Weber, a neuropathology colleague at Anapath, were performing immunostaining on rat astrocytomas and he supported Dr. Weber’s hypothesis that these tumors included a histiocytic component.

One of the most beautiful experiences I recall is when Dr. Krinke was contributing to a recent STP position paper for sampling and processing tissues of the peripheral nervous system (PNS).1 When the paper was accepted, Georg sent an email to the rest of the neuropathologists listed as authors, stating that this was his final contribution in our field and that he was officially retiring. Ironically, his retirement did not happen, as he continued his coauthoring contributions on three more manuscripts for the special forthcoming (2020) Toxicologic Pathology issue on toxicologic neuropathology of the PNS. He also served as an expert manuscript reviewer for several papers that will be included in that special issue, finishing the last just before his passing.

We in the neuropathology community are going to miss Dr. Krinke’s passion, love, enthusiasm, teaching, mentoring, open mind, and wisdom. My hope is that Georg’s legacy in the neuropathology field will continue through the ongoing efforts of colleagues who influence the Society by following Georg’s life-long tradition of service.

Love,
Ingrid D. Pardo

Reference

1. Bolon B, Krinke G, Butt MT, Rao DB, Pardo ID, Jortner BS, Garman RH, Jensen K, Andrews-Jones L, Morrison JP, Sharma AK, Thibodeau MK (2018). STP position paper: Recommended best practices for sampling, processing and analysis of the peripheral nervous system (nerves and somatic and autonomic ganglia) during nonclinical toxicity studies. Toxicol Pathol 46: 372–402.

On July 30th, 2018, Dr. Gordon P. Flake passed away at home. He is survived by his wife of 45 years, Cristina; five children, Stuart, Margo, Mandy, Heather and Derek; 10 grandchildren, Atlas, Ann Marie, Betsy, Nina, Elie, Haven, Maya, Tyler, Sophia and Logan; his brothers, Dickson Flake (Linda) and John Flake (Karen), and nieces, Lesley, Jessica and Rebecca.

Dr. Flake was born on Dec. 17, 1940, grew up in Little Rock and attended Little Rock Central High School. He continued his education at Johns Hopkins Undergraduate School where he was elected to Phi Beta Kappa, and Vanderbilt Medical School where he graduated first in his class. His pathology residency included three years at Vanderbilt, two years at the University of Minnesota, and one year at MD Anderson Center in Houston. He practiced pathology for two years in Panama while in the Army Medical Corps during the Vietnam War. There he met the love of his life, Cristina Quiros, and married in May 1973. He practiced for two years in Huntsville, AL, and 20 years in New Orleans, La., before moving to Chapel Hill in 1996, where he worked for 20 years at the National Institute of Environmental Health Sciences (NIEHS).

He loved his job at NIEHS in the department of Cellular and Molecular Pathology. He enjoyed talking to his colleagues, learning each day, and contributing to their studies. He loved all of the people in his department; and in his mind, they were part of his family. Other than his family, his work was his life. He considered everybody in the Institute a friend, including security guards, cafeteria staff, and housekeeping, and he appreciated their friendship. He felt blessed to work at such an interesting place with so many smart, dedicated people.

In the words of his co-workers at NIEHS: "We considered Gordon to be a best friend and colleague to everyone, no matter your position or status at the Institute. He was well-respected for his intellect, detailed approach to his work, and his sound contributions to science and public health, in particular his seminal research on the pathogenesis of uterine fibroids, and his numerous co-authorships on government reports, manuscripts, and book chapters. He was admired for his devotion to Cristina, Derek, and his family. We will always remember his love for baseball trivia, the Kentucky Derby and of course, UNC basketball despite not ever watching an entire game on TV. We at NIEHS will always remember Gordon as a gentleman, humble and kind; we all considered him our true friend and we would be honored if he felt the same way about us. Gordon will be truly missed at NIEHS."

The kind of research conducted by Dr. Flake, which led to his recognition as a world expert, is noted in the article, "Etiology and pathogenesis of uterine leiomyomas: a review," which up to this date has been cited 567 times. In later research on this subject he coined the word "inanosis," which is now included in medical lexicon.

There will be a private graveside funeral for the family in Chapel Hill on Monday, August 6th. A Celebration of Life Memorial for friends and family will be held on Saturday, August 11 from 4-7 p.m. at Extraordinary Ventures in Chapel Hill. If anyone wishes to contribute to a charity in honor of Dr. Flake, charities of his choosing include the Special Olympics of North Carolina, Extraordinary Ventures of Chapel Hill, and The Arc of the Triangle. The Flake family is being assisted by Walker's Funeral Home of Chapel Hill.

Published August 8, 2018

Dr. Daniel Morton, 59, died on September 30, 2015, in Columbus, OH, following a long battle with cancer. He was a preeminent toxicologic and veterinary pathologist and laboratory animal veterinarian with a distinguished career marked by significant scientific contributions, a lasting global influence on drug safety assessment and, especially, a lifelong service to the American College of Veterinary Pathologists (ACVP), the American College of Laboratory Animal Medicine (ACLAM), and the Society of Toxicologic Pathologists (STP). He graduated from Montana State University in 1978, with a degree in agriculture production. He received his DVM from Colorado State University in 1983, his MS degree in veterinary pathology from The Ohio State University in 1985 and his PhD in veterinary medical science from the University of Illinois in 1990. He was a diplomate of both ACLAM and ACVP. Following completion of his PhD program, he served as a clinical assistant professor and assistant director, Office of Laboratory Animal Care, University of Illinois from 1989 to 1993. He then moved to the Chicago area where he first served as a senior research scientist at Baxter Healthcare Corporation from 1993 to 1994 and then as a veterinary pathologist at Abbot Laboratories from 1994 to 1998. In 1998, he joined G. D. Searle in Skokie, IL, which in 2000 merged with Pharmacia and Upjohn to become Pharmacia Corporation. During his time at Searle and Pharmacia, he advanced from an assistant director to director and pathology site head. In 2003, Morton joined Pfizer following its acquisition of Pharmacia, moving to the Pfizer site in Groton Connecticut and subsequently to the Cambridge (afterward Andover) sites in Massachusetts. He served as an associate research fellow and a research fellow at Pfizer.

Morton was a pioneer and thought leader in toxicologic and comparative pathology and drug safety risk assessment. Of particular significance was his contributions to carcinogenicity assessment. He led a sustained international effort over 2 decades, promoting the development of alternatives to the 2-year rodent carcinogenicity bioassay. His work ultimately altered scientific and regulatory thinking regarding these bioassays, with resultant reduction in the cost of drug development, more accurate carcinogenicity bioassays, and the reduction in animals used for carcinogenicity assessment of drug candidates. Morton also served the veterinary pathology and laboratory animal medicine communities in his career. He served in key leadership roles in the ACVP, including examination committee member and chair, chair of the role delineation task force, and as a member of the strategic planning committee. He served on the ACVP Certification Examination Board since its inception in 2011 through 2014 and served as a member of the Certifying Examination Redesign Committee from 2014 until his death. Concurrently, Dan served in a number of senior leadership positions in the STP, serving first as the secretary/treasurer and then as president. He also served many roles for the ACLAM, including stints on the examination committee, with service as chair, and on the training program recognition committee. Dr. Morton received a number of awards and recognitions during his career. In 2008, he received the Presidential Award from the ACVP for his leadership and vision in designing and completing the College’s first role delineation study. In 2013, he received the Pfizer Worldwide Research and Development Achievement Award for his body of work related to nonclinical carcinogenicity assessment. In 2014, he received STP’s Lifetime Achievement Award for his many contributions both to the organization and to the advancement of toxicologic pathology. In 2015, he was selected as a distinguished member of the ACVP. The last two awards are the highest awards given by these two professional organizations.

Dan’s most lasting contributions to his profession lie in his vision, his relentless pursuit of what he believed to be right, his challenge of the status quo, and his mentorship of those who worked with him. Dan was the epitome of the quiet leader: he led not through the force of his ego but by his thoughts and actions. He elevated the people around him, gave credit for successes rather than taking it, and accepted personal responsibility instead of directing blame at others. His effective leadership was influenced by his intelligence, kindness, integrity, and ability to generate consensus. Dan helped to guide a generation of toxicologic pathologists and the void that his death has left will be felt by many. Survivors include his wife of 31 years, Laura Dill Morton, and two sons John Parker Morton and Mathew George Morton. Dan is also survived by his father, George Morton, his brother Ken (Diane) Morton, and his sister Lynne (Tom) Champitto. He was predeceased by his mother Betty Morton. He is also survived by his father- and motherin-law Garrett (Sidney) Dill; brothers-in-law Brian (Marcie) Dill and Matt (Shannon) Dill; nieces Jenn (Miles) Hubbs and Caitlin Dill; and nephews Scott Morton, Michael Dill, Aaron Dill, and Tyler Dill.

Bobby passed with peace and grace on March 8, 2015 at his home with his wife.

Bobby was born December 23, 1931 in Kilbourne, Louisiana. He graduated from Texas A&M University in veterinary medicine in 1956 and in 1960 he earned his masters in veterinary pathology. In 1965, he completed his PhD from University of Minnesota in veterinary pathology with a minor in physical chemistry.

He spent two years in Bangladesh teaching pathology for the Armed Forces Institute of Pathology. He started his career as an assistant professor at MIT, and then successfully moved into industry as a preclinical toxicologic pathologist in drug development at Smith Kline French before moving into managing, consulting, and owning his own research laboratory. He retired in 2010 after a brief period as a visiting professor in Kuala Lumpur, Malaysia.

Bobby enjoyed riding his horses and outdoor projects—clearing land, cutting trees and experimental landscaping. He was married to CJ Reynolds in Bethesda, Maryland on April 1, 1999. He is survived by his wife, brother, sister-in-law, and two children.

The family requests that any donations be made to the college scholarship fund of your choice.

Asa Harris Mosher, 78, of Salford Township, Pennsylvania passed away at his residence on Wednesday, August 27, 2014, surrounded by his loving family. Born in Cranford, New Jersey, he was the son of the late Byron J. and Dorothy Ruth (Harris) Mosher. He was employed as a veterinary pathologist for Johnson & Johnson Pharmaceuticals for 27 years prior to his retirement in 1998. Following high school, he graduated from the University of Delaware in 1958, the University of Pennsylvania School of Veterinary Medicine in 1962, and earned his PhD in 1968 from the University of Connecticut.

Dr. Mosher was a member of the Presbyterian Church of Deep Run. He was also a member of the American Academy of Veterinary Pathologists, the Farm Preservation Board of Montgomery County, the North American Limousin Foundation, and the Salford Township Zoning Hearing Board. He enjoyed being outside and spending time with his cows, and was known for having one of the largest full-blood Limousin herds in the country. One of his greatest enjoyments was spending time with his grandchildren and attending their sporting events. He himself was the last person to letter in three sports at the University of Delaware.

In addition to his wife Marjorie (Staub) Mosher, he is survived by a daughter and two sons, their spouses and eight grandchildren.

John M. Pletcher, DVM, MPH, DACVP, passed away on September 16 after a brave battle with pancreatic cancer. John made significant contributions to many aspects of veterinary pathology during two separate, distinct careers.

He earned a Bachelor of Science degree in 1967 followed by a Doctor of Veterinary Medicine degree in 1969. Upon graduation, John began his active duty career in the US Air Force Veterinary Service, a career that would ultimately have profound effects on the field of veterinary pathology. After a year as Base Veterinarian at Lakeland Air Force Base, he was assigned to a post at the University of Michigan, Ann Arbor, where he received his Master of Public Health degree in 1971. He later completed a residency in veterinary pathology at the Armed Forces Institute of Pathology (AFIP) and was certified by the American College of Veterinary Preventive Medicine in 1977, and certified in anatomic pathology by the American College of Veterinary Pathology (ACVP) in 1979. Working as a staff pathologist at the Onderstepoort Veterinary Research Institute and as a research pathologist at Kruger National Wildlife Park, Republic of South Africa from 1979 to 1982, John authored or co-authored many scientific papers and commentaries on infectious and parasitic diseases in South African wildlife. As Chairman of the AFIP Department of Veterinary Pathology from 1986 to 1992, John’s duties included the management of veterinary pathology consults from around the world, research in numerous aspects of veterinary pathology, and the training of veterinary pathologists for the US Army and US Air Force. Also during that time, John directed the pathology support of the US Fisheries and Wildlife Service during their evaluation of the Exxon Valdez oil spill from 1989 to 1990, and organized research aimed at evaluating the effects of oil fire smoke on animals following the Kuwaiti oil fires in 1991. While John authored or co-authored numerous journal articles on a wide spectrum of veterinary pathology during his term as Chairman at the AFIP, his professional attention focused on strengthening the AFIP veterinary pathology program and mentoring trainees. Graduates of AFIP’s residency program have made a significant impact in all aspects of veterinary pathology in the US military services and other government agencies, academia, and industry. John retired as a Colonel from the United States Army Veterinary Corps (having transferred from the Air Force) in 1992 and entered his second career with Pathology Associates, Inc. (PAI) after a distinguished 23-year career in the military. During his 21 years with PAI (now Charles River Laboratories-Pathology Associates), John’s publications and contributions to toxicologic pathology were as equally impressive as his contributions to research, education, and military service. In addition to providing pathology services to the pharmaceutical industry, the US Food and Drug Administration, the US Environmental Protection Agency, the National Institute of Environmental Health Sciences, and numerous other PAI clients, John supervised a large group of veterinary pathologists and staff. In this regard, John was a cornerstone of science, morale, mentoring and professionalism. At the time of John’s passing he was a Senior Scientific Director with Charles River Laboratories.

John was a long-time member of the Society of Toxicologic Pathology and served as a member of the Standardization of Nomenclature and Diagnostic Criteria Program (1989–1992). He was also a member of the American College of Veterinary Pathologists (ACVP), where he served as a member of the examination committee (1984–1988) and a Councilor (1992–1995).

Dr. Pletcher is survived by Suzanne Pletcher, his wife of 43 years, two adult children, and three grandchildren.

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BIO UNAVAILABLE

Professor Yoichi Konishi, an STP member and a distinguished pathologist who contributed to the field of cancer research for several decades, passed away on December 21. He consistently worked on basic research to elucidate mechanisms by which cancers develop and on ways to prevent this deadly disease. He published numerous papers in major scientific journals and was particularly well known as an expert on pancreatic carcinogenesis. He was awarded the Princess Takamatsu Cancer Research Fund Prize in 2000.

Professor Konishi also contributed to the activities of a variety of scientific societies and frequently organized scientific meetings, both international and domestic. Among those, it is noteworthy that he was the president of the IFSTP and organized its international meeting. He was also instrumental in establishing the IATP and served as a regional director for the Asia/Pacific Region.

Dr. John F. Van Vleet, a long time STP member and Professor Emeritus at Purdue University, died January 5. Dr. Van Vleet received his DVM degree from Cornell University in 1962, an MS in Veterinary Pathology from the University of Illinois in 1965, and his PhD in Veterinary Pathology from the University of Illinois in 1967. He also received his board certification from the American College of Veterinary Pathologists in 1967. That same year, Dr. Van Vleet came to Purdue University as a Professor of Veterinary Pathology and in 1988, he was appointed the Associate Dean for Academic Affairs in the School of Veterinary Medicine, retiring in 2010. During his entire tenure at Purdue, he was in the classroom, educating and mentoring students. Since 2001, he had served as a visiting professor at St. George’s University in Grenada, West Indies. Dr. Van Vleet received numerous honors and awards including the Norden Award of Outstanding Instructor in the School of Veterinary Medicine and he was chosen to be included in the Book of Great Teachers at Purdue University for excellence in the classroom. Dr. Van Vleet was internationally recognized for his many contributions to toxicologic pathology and specifically to cardiovascular disease with over 140 publications in his areas of expertise. He contributed chapters to all major veterinary pathology and toxicologic pathology textbooks, including the "Handbook of Toxicologic Pathology", and served as a consultant for pharmaceutical, biotechnology, and medical device companies. Dr. Van Vleet was published in various pathology journals and textbooks. He is survived by his wife Nancy.

Dr. Ronna Fulton, age 51, died peacefully at home in Birmingham, Alabama on Wednesday, February 22, 2012, after a 6+ year battle with metastatic breast cancer.
Ronna was born on July 14, 1960, in Ft. Collins, Colorado to Betty Folsom and Hugh Thompson Fulton.

She attended Cape Girardeau, Missouri Central High School (Class of 1978). She completed her Bachelor of Science in Agriculture and Biochemistry from the University of Missouri in 1982. She then went on to get her Doctorate of Veterinary Medicine from University of Missouri in 1985. She was awarded her PhD in Veterinary Pathology in 1991 from Colorado State University, and became a Diplomate (Clinical Veterinary Pathology) of the American College of Veterinary Pathologists in 1993.

She worked as Veterinarian for the Terra Veterinary Clinic in Lebanon, Missouri between 1985 an 1986. She was a Clinical Pathology Resident at the University of Florida, Gainesville, Florida, between 1986 and 1987 and at Colorado State University between 1987 and 1991. After obtaining her PhD, she taught Clinical Pathology at Colorado State University, and went on to two postdoctoral positions. The first was a Pulmonary Postdoctoral Research Fellowship at the National Jewish Medical and Research Center in Denver, Colorado, and the second was a Veterinary Clinical Pathology Consultant at Colorado Animal Research Enterprises, Fort Collins, Colorado. In 1996, she accepted a position as the Manager of Clinical Pathology at Southern Research Institute in Birmingham, Alabama. She went on to become Staff Senior Clinical Pathologist in 2002. In 2007, Ronna formed her own company, Fulton Veterinary Clinical Pathology Consulting, LLC.

Ronna loved to read and to travel. She loved the outdoors, whether that was the beach, the mountains, a sunrise or sunset. She loved Native American history, art and architecture. She was a smart, practical, loving wife, mother and friend. Her courage and sheer determination to live as long as possible will never be forgotten. She will be greatly missed by all who knew and loved her.

Ronna is survived by her husband, James Nietfeld; her children, Wesley (b. 1994) and Collin (b. 1997); her mother, Betty Folsom Fulton and her sister, Anne Fulton McIntyre.

Her memorial service was held at Asbury United Methodist Church in Birmingham, Alabama on Monday February 27, 2012, at 7:30 pm In lieu of flowers, Ronna asked that donations be made to St. Vincent’s—Bruno Cancer Center in Birmingham, Alabama.

William (Bill) M. Busey, DVM, PhD, a longtime STP Member and co-founder of EPL, Inc., died on August 6, 2011, in Vienna, Virginia. Dr. Busey was instrumental in designing and developing pathology peer review procedures and approaches, which are used by the NTP and many companies worldwide. He co-founded EPL Pathology Archives, Inc. in 1978, nearly a year before the preservation of research materials was mandated by law by the U.S. FDA.

Dr. Busey is survived by his wife Betty; two children, and six grandchildren. Memorial services were held Saturday, August 13 at Immanuel Presbyterian Church, McLean, Virginia. In lieu of flowers, contributions can be made to The Ohio State University-College of Veterinary Medicine, 1900 Coffey Rd., Columbus, Ohio 43210 or the Grear Memorial Garden at Immanuel Presbyterian Church, 1125 Savile Lane, McLean, Virginia 22101.